Guofang Chen

Shanghai Key Laboratory Of Maternal Fetal Medicine
Shanghai, 200092, China

Last Updated: 09/26/2026

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Found 20 publications

Genomic characterization of uterine adenomatoid tumors reveals recurrent alterations in KMT5A and KMT2C.

Genomic characterization of uterine adenomatoid tumors reveals recurrent alterations in KMT5A and KMT2C.

Journal: Clinical epigenetics

Published: November 18, 2025

Lamins regulate cancer cell plasticity and chemosensitivity.

Lamins regulate cancer cell plasticity and chemosensitivity.

Journal: Frontiers in oncology

Published: March 31, 2025

Drug screening identifies pyrrolidinedithiocarbamate ammonium ameliorating DSS-induced mouse ulcerative colitis via suppressing Th17 differentiation.

Drug screening identifies pyrrolidinedithiocarbamate ammonium ameliorating DSS-induced mouse ulcerative colitis via suppressing Th17 differentiation.

Journal: Cellular immunology

Published: August 26, 2024

Combined therapy of dabrafenib and an anti-HER2 antibody-drug conjugate for advanced BRAF-mutant melanoma.

Combined therapy of dabrafenib and an anti-HER2 antibody-drug conjugate for advanced BRAF-mutant melanoma.

Journal: Cellular & molecular biology letters

Published: November 06, 2023

SIRT7 facilitates endometrial cancer progression by regulating PTEN stability in an estrogen-dependent manner.

SIRT7 facilitates endometrial cancer progression by regulating PTEN stability in an estrogen-dependent manner.

Journal: Nature communications

Published: September 26, 2023

Combined inhibition of HER2 and VEGFR synergistically improves therapeutic efficacy via PI3K-AKT pathway in advanced ovarian cancer.

Combined inhibition of HER2 and VEGFR synergistically improves therapeutic efficacy via PI3K-AKT pathway in advanced ovarian cancer.

Journal: Journal of experimental & clinical cancer research : CR

Published: September 16, 2023

The P286R mutation of DNA polymerase ε activates cancer-cell-intrinsic immunity and suppresses endometrial tumorigenesis via the cGAS-STING pathway.

The P286R mutation of DNA polymerase ε activates cancer-cell-intrinsic immunity and suppresses endometrial tumorigenesis via the cGAS-STING pathway.

Journal: Cell death & disease

Published: June 28, 2023

SMYD2 inhibition-mediated hypomethylation of Ku70 contributes to impaired nonhomologous end joining repair and antitumor immunity.

SMYD2 inhibition-mediated hypomethylation of Ku70 contributes to impaired nonhomologous end joining repair and antitumor immunity.

Journal: Science advances

Published: June 14, 2023

Protein quality control and aggregation in the endoplasmic reticulum: From basic to bedside.

Protein quality control and aggregation in the endoplasmic reticulum: From basic to bedside.

Journal: Frontiers in cell and developmental biology

Published: February 02, 2023

SMYD3 promotes endometrial cancer through epigenetic regulation of LIG4/XRCC4/XLF complex in non-homologous end joining repair.

SMYD3 promotes endometrial cancer through epigenetic regulation of LIG4/XRCC4/XLF complex in non-homologous end joining repair.

Journal: Oncogenesis

Published: January 22, 2023

Histone Deacetylase 3 Governs β-Estradiol-ERα-Involved Endometrial Tumorigenesis via Inhibition of STING Transcription.

Histone Deacetylase 3 Governs β-Estradiol-ERα-Involved Endometrial Tumorigenesis via Inhibition of STING Transcription.

Journal: Cancers

Published: August 11, 2022

CRISPR-Based Therapeutic Gene Editing for Duchenne Muscular Dystrophy: Advances, Challenges and Perspectives.

CRISPR-Based Therapeutic Gene Editing for Duchenne Muscular Dystrophy: Advances, Challenges and Perspectives.

Journal: Cells

Published: August 11, 2022

Showing 1-12 of 20

Last Updated: 09/26/2026