Guoning P. Zhang

Chinese Academy Of Medical Sciences & Peking Union Medical College
Beijing, 100050, China

Last Updated: 09/26/2026

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Found 33 publications

Design, synthesis and antibacterial activity of novel LpxC inhibitors containing 1,2,3-triazole moieties.

Design, synthesis and antibacterial activity of novel LpxC inhibitors containing 1,2,3-triazole moieties.

Journal: Bioorganic & medicinal chemistry letters

Published: January 05, 2026

Design, Synthesis, and Biological Evaluation of Novel Core Scaffold-Modified HIV-1 Protease Inhibitors for Overcoming Drug Resistance.

Design, Synthesis, and Biological Evaluation of Novel Core Scaffold-Modified HIV-1 Protease Inhibitors for Overcoming Drug Resistance.

Journal: Journal of medicinal chemistry

Published: October 22, 2025

Rational design, synthesis, and evaluating primary biological activities of novel HIV-1 protease inhibitors containing heteraryl acetamides as the P2 ligands.

Rational design, synthesis, and evaluating primary biological activities of novel HIV-1 protease inhibitors containing heteraryl acetamides as the P2 ligands.

Journal: Bioorganic & medicinal chemistry

Published: May 21, 2025

Novel Oxazolidinone Derivatives Containing Quaternary Ammonium Fragments with Potent Antibacterial Potency.

Novel Oxazolidinone Derivatives Containing Quaternary Ammonium Fragments with Potent Antibacterial Potency.

Journal: ACS medicinal chemistry letters

Published: May 21, 2025

Discovery and rational optimization of 2, 2'-((1H-indole-2,3-diyl) bis (thio))diacetamide as novel SARS-CoV-2 RdRp inhibitors.

Discovery and rational optimization of 2, 2'-((1H-indole-2,3-diyl) bis (thio))diacetamide as novel SARS-CoV-2 RdRp inhibitors.

Journal: Bioorganic & medicinal chemistry

Published: January 02, 2025

Promotion and implementation of respiratory syncytial virus monoclonal antibody in vaccination clinics in Tianjin City

Promotion and implementation of respiratory syncytial virus monoclonal antibody in vaccination clinics in Tianjin City

Journal: Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]

Published: November 28, 2024

Discovery and optimization of phenazopyridine hydrochloride as novel SARS-CoV-2 RdRp inhibitors.

Discovery and optimization of phenazopyridine hydrochloride as novel SARS-CoV-2 RdRp inhibitors.

Journal: European journal of medicinal chemistry

Published: November 24, 2024

Synthesis and biological evaluation of substituted quinolines containing piperazine moieties against Influenza A virus.

Synthesis and biological evaluation of substituted quinolines containing piperazine moieties against Influenza A virus.

Journal: Bioorganic & medicinal chemistry letters

Published: July 23, 2024

Discovery and development of benzene sulfonamide derivatives as anti-hepatic fibrosis agents.

Discovery and development of benzene sulfonamide derivatives as anti-hepatic fibrosis agents.

Journal: Bioorganic & medicinal chemistry letters

Published: January 28, 2023

Design, synthesis, and biological evaluation of novel HIV-1 protease inhibitors containing pyrrolidine-derived P2 ligands to combat drug-resistant variant.

Design, synthesis, and biological evaluation of novel HIV-1 protease inhibitors containing pyrrolidine-derived P2 ligands to combat drug-resistant variant.

Journal: European journal of medicinal chemistry

Published: January 04, 2023

New IMB16-4 Hot-Melt Extrusion Preparation Improved Oral Bioavailability and Enhanced Anti-Cholestatic Effect on Rats.

New IMB16-4 Hot-Melt Extrusion Preparation Improved Oral Bioavailability and Enhanced Anti-Cholestatic Effect on Rats.

Journal: Drug design, development and therapy

Published: October 27, 2022

The mechanism and pharmacodynamics of 2-((1H-indol-3-yl)thio/sulfinyl)-N-pheny acetamide derivative as a novel inhibitor against human respiratory syncytial virus.

The mechanism and pharmacodynamics of 2-((1H-indol-3-yl)thio/sulfinyl)-N-pheny acetamide derivative as a novel inhibitor against human respiratory syncytial virus.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: September 22, 2022

Showing 1-12 of 33

Last Updated: 09/26/2026