Gyula Palfy

Budapest, BU, Hungary

Last Updated: 09/26/2026

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Found 17 publications

Analysis of the structure and interactions of the SARS-CoV-2 ORF7b accessory protein.

Analysis of the structure and interactions of the SARS-CoV-2 ORF7b accessory protein.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: November 07, 2024

Mapping protein binding sites by photoreactive fragment pharmacophores.

Mapping protein binding sites by photoreactive fragment pharmacophores.

Journal: Communications chemistry

Published: June 01, 2024

NMR-Chemical-Shift-Driven Protocol Reveals the Cofactor-Bound, Complete Structure of Dynamic Intermediates of the Catalytic Cycle of Oncogenic KRAS G12C Protein and the Significance of the Mg2+ Ion.

NMR-Chemical-Shift-Driven Protocol Reveals the Cofactor-Bound, Complete Structure of Dynamic Intermediates of the Catalytic Cycle of Oncogenic KRAS G12C Protein and the Significance of the Mg2+ Ion.

Journal: International journal of molecular sciences

Published: June 30, 2023

Covalent fragment mapping of KRasG12C revealed novel chemotypes with in vivo potency.

Covalent fragment mapping of KRasG12C revealed novel chemotypes with in vivo potency.

Journal: European journal of medicinal chemistry

Published: September 21, 2022

The Importance of Mg2+ -Free State in Nucleotide Exchange of Oncogenic K-Ras Mutants.

The Importance of Mg2+ -Free State in Nucleotide Exchange of Oncogenic K-Ras Mutants.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)

Published: May 10, 2022

Structural impact of GTP binding on downstream KRAS signaling.

Structural impact of GTP binding on downstream KRAS signaling.

Journal: Chemical science

Published: June 07, 2021

Investigating thermal stability based on the structural changes of lactase enzyme by several orthogonal methods.

Investigating thermal stability based on the structural changes of lactase enzyme by several orthogonal methods.

Journal: Biotechnology reports (Amsterdam, Netherlands)

Published: April 20, 2021

Assessment of Tractable Cysteines for Covalent Targeting by Screening Covalent Fragments.

Assessment of Tractable Cysteines for Covalent Targeting by Screening Covalent Fragments.

Journal: Chembiochem : a European journal of chemical biology

Published: October 08, 2020

Bacterial fermentation and isotope labelling optimized for amyloidogenic proteins.

Bacterial fermentation and isotope labelling optimized for amyloidogenic proteins.

Journal: Microbial biotechnology

Published: September 08, 2020

Tumor-Suppressor p53TAD1-60 Forms a Fuzzy Complex with Metastasis-Associated S100A4: Structural Insights and Dynamics by an NMR/MD Approach.

Tumor-Suppressor p53TAD1-60 Forms a Fuzzy Complex with Metastasis-Associated S100A4: Structural Insights and Dynamics by an NMR/MD Approach.

Journal: Chembiochem : a European journal of chemical biology

Published: June 02, 2020

Dynamically encoded reactivity of Ras enzymes: opening new frontiers for drug discovery.

Dynamically encoded reactivity of Ras enzymes: opening new frontiers for drug discovery.

Journal: Cancer metastasis reviews

Published: May 22, 2020

Allele-specific inhibitors of mutant KRAS are in the focus of RASopathy consortium

Allele-specific inhibitors of mutant KRAS are in the focus of RASopathy consortium

Journal: Magyar onkologia

Published: November 24, 2019

Showing 1-12 of 17

Last Updated: 09/26/2026