Hamish D. Toop
Milton Science Park
Cambridge, ENG, United Kingdom
Cambridge, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 15 publications
Use of modulators and light to control crystallisation of a hydrogen bonded framework.
Journal: Chemical communications (Cambridge, England)
Published: December 10, 2021
Shwachman-Bodian-Diamond syndrome (SBDS) protein is a direct inhibitor of protein phosphatase 2A (PP2A) activity and overexpressed in acute myeloid leukaemia.
Journal: Leukemia
Published: July 04, 2019
TRAIL signals through the ubiquitin ligase MID1 to promote pulmonary fibrosis.
Journal: BMC pulmonary medicine
Published: December 21, 2017
A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism.
Journal: Nature communications
Published: September 07, 2017
Concise Total Synthesis of Dioncophylline E through an ortho-Arylation Strategy.
Journal: Angewandte Chemie (International ed. in English)
Published: February 01, 2017
Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease.
Journal: ACS chemical biology
Published: January 31, 2017
Development of novel PP2A activators for use in the treatment of acute myeloid leukaemia.
Journal: Organic & biomolecular chemistry
Published: April 23, 2016
Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors.
Journal: Oncotarget
Published: April 07, 2016
Synthesis and biological evaluation of analogs of AAL(S) for use as ceramide synthase 1 inhibitors.
Journal: Organic & biomolecular chemistry
Published: November 05, 2015
Tumor necrosis factor-related apoptosis-inducing ligand regulates hallmark features of airways remodeling in allergic airways disease.
Journal: American journal of respiratory cell and molecular biology
Published: February 04, 2014
Last Updated: 09/26/2026