Han S. Wu

CAS Key Laboratory Of Regenerative Biology, Guangdong Provincial Key Laboratory Of Stem Cell And Regenerative Medicine
Guangzhou, 510530, China

Last Updated: 09/26/2026

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Found 17 publications

A-to-G/C/T and C-to-T/G/A dual-function base editor for creating multi-nucleotide variants.

A-to-G/C/T and C-to-T/G/A dual-function base editor for creating multi-nucleotide variants.

Journal: Journal of genetics and genomics = Yi chuan xue bao

Published: May 01, 2024

In vivo evaluation of guide-free Cas9-induced safety risks in a pig model.

In vivo evaluation of guide-free Cas9-induced safety risks in a pig model.

Journal: Signal transduction and targeted therapy

Published: September 14, 2023

Precise genome editing of the Kozak sequence enables bidirectional and quantitative modulation of protein translation to anticipated levels without affecting transcription.

Precise genome editing of the Kozak sequence enables bidirectional and quantitative modulation of protein translation to anticipated levels without affecting transcription.

Journal: Nucleic acids research

Published: October 25, 2022

Multiplexed base editing through Cas12a variant-mediated cytosine and adenine base editors.

Multiplexed base editing through Cas12a variant-mediated cytosine and adenine base editors.

Journal: Communications biology

Published: June 26, 2022

Pathological Responses of the Primary Tumor and Locoregional Lymph Nodes After Neoadjuvant Immunochemotherapy in Esophageal Squamous Cell Cancer.

Pathological Responses of the Primary Tumor and Locoregional Lymph Nodes After Neoadjuvant Immunochemotherapy in Esophageal Squamous Cell Cancer.

Journal: World journal of oncology

Published: May 06, 2022

Double knock-in pig models with elements of binary Tet-On and phiC31 integrase systems for controllable and switchable gene expression.

Double knock-in pig models with elements of binary Tet-On and phiC31 integrase systems for controllable and switchable gene expression.

Journal: Science China. Life sciences

Published: November 05, 2021

CRISPR/Cas9-mediated β-globin gene knockout in rabbits recapitulates human β-thalassemia.

CRISPR/Cas9-mediated β-globin gene knockout in rabbits recapitulates human β-thalassemia.

Journal: The Journal of biological chemistry

Published: September 22, 2020

ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems.

ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems.

Journal: BMC biology

Published: April 01, 2020

Improving the Cpf1-mediated base editing system by combining dCas9/dead sgRNA with human APOBEC3A variants.

Improving the Cpf1-mediated base editing system by combining dCas9/dead sgRNA with human APOBEC3A variants.

Journal: Journal of genetics and genomics = Yi chuan xue bao

Published: January 21, 2020

Engineered Pigs Carrying a Gain-of-Function NLRP3 Homozygous Mutation Can Survive to Adulthood and Accurately Recapitulate Human Systemic Spontaneous Inflammatory Responses.

Engineered Pigs Carrying a Gain-of-Function NLRP3 Homozygous Mutation Can Survive to Adulthood and Accurately Recapitulate Human Systemic Spontaneous Inflammatory Responses.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: December 12, 2019

In vivo genome editing in mouse restores dystrophin expression in Duchenne muscular dystrophy patient muscle fibers.

In vivo genome editing in mouse restores dystrophin expression in Duchenne muscular dystrophy patient muscle fibers.

Journal: Genome medicine

Published: August 21, 2019

Generation of two MEN1 knockout lines from a human embryonic stem cell line.

Generation of two MEN1 knockout lines from a human embryonic stem cell line.

Journal: Stem cell research

Published: May 10, 2017

Showing 1-12 of 17

Last Updated: 09/26/2026