Han Yao

State Key Laboratory Of Anti Infective Drug Discovery And Development, Guangdong Provincial Key Laboratory Of Chiral Molecule And Drug Discovery
Guangzhou, 510006, China

Last Updated: 09/26/2026

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Found 24 publications

A novel c-Met inhibitor containing chiral pyrrolidine side chain and its application as anti-tumor agents.

A novel c-Met inhibitor containing chiral pyrrolidine side chain and its application as anti-tumor agents.

Journal: European journal of medicinal chemistry

Published: March 02, 2026

The synthesis and biological evaluation of novel deuterated and non-deuterated aminobenzenesulfonamide derivatives as EGFR inhibitor.

The synthesis and biological evaluation of novel deuterated and non-deuterated aminobenzenesulfonamide derivatives as EGFR inhibitor.

Journal: Bioorganic & medicinal chemistry

Published: February 04, 2026

Toddacoumalins A-J, ten undescribed coumarins from the roots of Toddalia asiatica.

Toddacoumalins A-J, ten undescribed coumarins from the roots of Toddalia asiatica.

Journal: Phytochemistry

Published: December 29, 2025

Synthesis and evaluation of methoxyquinazoline sulfonamide derivatives as bifunctional molecular targeting tumor related inflammation and anti-EGFR triple-mutation.

Synthesis and evaluation of methoxyquinazoline sulfonamide derivatives as bifunctional molecular targeting tumor related inflammation and anti-EGFR triple-mutation.

Journal: Bioorganic chemistry

Published: December 17, 2025

The synthesis and evaluation of new N-(pyrazin-2-yl)-4-aminopyrimidine derivatives targeted EGFR and JAK.

The synthesis and evaluation of new N-(pyrazin-2-yl)-4-aminopyrimidine derivatives targeted EGFR and JAK.

Journal: European journal of medicinal chemistry

Published: July 13, 2025

Synthesis and evaluation of new 5-(1H-1,2,4-triazol-3-yl)-1,2,4-oxadiazole derivatives and their application as OXPHOS inhibitors.

Synthesis and evaluation of new 5-(1H-1,2,4-triazol-3-yl)-1,2,4-oxadiazole derivatives and their application as OXPHOS inhibitors.

Journal: European journal of medicinal chemistry

Published: April 22, 2025

Synthesis and evaluation of novel amino pyrimidine derivatives containing sulfonamide and their application as EGFR inhibitors.

Synthesis and evaluation of novel amino pyrimidine derivatives containing sulfonamide and their application as EGFR inhibitors.

Journal: Bioorganic chemistry

Published: February 12, 2025

The Discovery of a Novel AXL/Triple Angiokinase Inhibitor Based on 6-Chloro-Substituted Indolinone and Side Chain Methyl Substitution Inhibiting Pancreatic Cancer Growth and Metastasis.

The Discovery of a Novel AXL/Triple Angiokinase Inhibitor Based on 6-Chloro-Substituted Indolinone and Side Chain Methyl Substitution Inhibiting Pancreatic Cancer Growth and Metastasis.

Journal: Journal of medicinal chemistry

Published: December 23, 2024

The new N2, N4-diphenylpyridine-2,4-diamine deuterated derivatives as EGFR inhibitors to overcome C797S-mediated resistance.

The new N2, N4-diphenylpyridine-2,4-diamine deuterated derivatives as EGFR inhibitors to overcome C797S-mediated resistance.

Journal: Bioorganic chemistry

Published: February 04, 2024

Discovery of new cyclopropane sulfonamide derivatives as EGFR inhibitors to overcome C797S-mediated resistance and EGFR double mutation.

Discovery of new cyclopropane sulfonamide derivatives as EGFR inhibitors to overcome C797S-mediated resistance and EGFR double mutation.

Journal: European journal of medicinal chemistry

Published: February 02, 2024

Regioselective Hydrodeoxygenation of α-Diketones with Phosphites under Visible-Light Catalysis.

Regioselective Hydrodeoxygenation of α-Diketones with Phosphites under Visible-Light Catalysis.

Journal: Organic letters

Published: October 02, 2023

A novel c-Met/TRK inhibitor 1D228 efficiently inhibits tumor growth by targeting angiogenesis and tumor cell proliferation.

A novel c-Met/TRK inhibitor 1D228 efficiently inhibits tumor growth by targeting angiogenesis and tumor cell proliferation.

Journal: Cell death & disease

Published: April 19, 2023

Showing 1-12 of 24

Last Updated: 09/26/2026