Hana Kunkel

Frankfurt Am Main, HE, Germany

Last Updated: 09/26/2026

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Found 12 publications

Non-Clinical Efficacy and Safety Studies on G1XCGD, a Lentiviral Vector for Ex Vivo Gene Therapy of X-Linked Chronic Granulomatous Disease.

Non-Clinical Efficacy and Safety Studies on G1XCGD, a Lentiviral Vector for Ex Vivo Gene Therapy of X-Linked Chronic Granulomatous Disease.

Journal: Human gene therapy. Clinical development

Published: April 18, 2018

Targeting HSP90 dimerization via the C terminus is effective in imatinib-resistant CML and lacks the heat shock response.

Targeting HSP90 dimerization via the C terminus is effective in imatinib-resistant CML and lacks the heat shock response.

Journal: Blood

Published: October 12, 2017

Suppression of RUNX1/ETO oncogenic activity by a small molecule inhibitor of tetramerization.

Suppression of RUNX1/ETO oncogenic activity by a small molecule inhibitor of tetramerization.

Journal: Haematologica

Published: February 04, 2017

Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer.

Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer.

Journal: Oncotarget

Published: October 13, 2016

Rapamycin and WYE-354 suppress human gallbladder cancer xenografts in mice.

Rapamycin and WYE-354 suppress human gallbladder cancer xenografts in mice.

Journal: Oncotarget

Published: May 12, 2015

A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells.

A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells.

Journal: Nucleic acids research

Published: January 22, 2015

CD133-targeted gene transfer into long-term repopulating hematopoietic stem cells.

CD133-targeted gene transfer into long-term repopulating hematopoietic stem cells.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: June 05, 2014

PGE2/EP4 signaling in peripheral immune cells promotes development of experimental autoimmune encephalomyelitis.

PGE2/EP4 signaling in peripheral immune cells promotes development of experimental autoimmune encephalomyelitis.

Journal: Biochemical pharmacology

Published: September 26, 2013

Prostacyclin mediates neuropathic pain through interleukin 1β-expressing resident macrophages.

Prostacyclin mediates neuropathic pain through interleukin 1β-expressing resident macrophages.

Journal: Pain

Published: July 25, 2013

From bench to bedside: preclinical evaluation of a self-inactivating gammaretroviral vector for the gene therapy of X-linked chronic granulomatous disease.

From bench to bedside: preclinical evaluation of a self-inactivating gammaretroviral vector for the gene therapy of X-linked chronic granulomatous disease.

Journal: Human gene therapy. Clinical development

Published: July 13, 2013

Alpharetroviral vector-mediated gene therapy for X-CGD: functional correction and lack of aberrant splicing.

Alpharetroviral vector-mediated gene therapy for X-CGD: functional correction and lack of aberrant splicing.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: December 05, 2012

Physiological regulation of transgene expression by a lentiviral vector containing the A2UCOE linked to a myeloid promoter.

Physiological regulation of transgene expression by a lentiviral vector containing the A2UCOE linked to a myeloid promoter.

Journal: Gene therapy

Published: November 11, 2011

Showing 1-12 of 12

Last Updated: 09/26/2026