Hanae Morio
Tokyo, 1920392, Japan
Last Updated: 09/26/2026
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Found 20 publications
Human blood-brain barrier spheroid models for the evaluation of drugs targeting brain vascular inflammation.
Journal: Journal of pharmacological sciences
Published: January 27, 2026
Translational applicability of human blood-brain barrier spheroid models for the development of brain-penetrant therapeutic antibodies.
Journal: Fluids and barriers of the CNS
Published: August 26, 2025
Functional assessment of immortalized human brain microvascular endothelial cells with different passage numbers: A case study for a prospective proposal on variability management of in vitro blood-brain barrier models.
Journal: Drug metabolism and pharmacokinetics
Published: September 12, 2024
Transferrin receptor-targeting property of pabinafusp alfa facilitates its uptake by various types of human brain-derived cells in vitro.
Journal: Frontiers in drug delivery
Published: October 28, 2022
Human Immortalized Cell-Based Blood-Brain Barrier Spheroid Models Offer an Evaluation Tool for the Brain Penetration Properties of Macromolecules.
Journal: Molecular pharmaceutics
Published: June 29, 2022
Generation of a Human Conditionally Immortalized Cell-based Multicellular Spheroidal Blood-Brain Barrier Model for Permeability Evaluation of Macromolecules.
Journal: Bio-protocol
Published: March 08, 2022
In Vitro-In Vivo Correlation of Blood-Brain Barrier Permeability of Drugs: A Feasibility Study Towards Development of Prediction Methods for Brain Drug Concentration in Humans.
Journal: Pharmaceutical research
Published: November 29, 2021
Evaluating a Targeted Cancer Therapy Approach Mediated by RNA trans-Splicing In Vitro and in a Xenograft Model for Epidermolysis Bullosa-Associated Skin Cancer.
Journal: International journal of molecular sciences
Published: October 28, 2021
Development, Characterization and Potential Applications of a Multicellular Spheroidal Human Blood-Brain Barrier Model Integrating Three Conditionally Immortalized Cell Lines.
Journal: Biological & pharmaceutical bulletin
Published: April 26, 2021
Effects of islatravir (4'-ethynyl-2-fluoro-2'-deoxyadenosine or EFdA) on renal tubular cells and islatravir's interactions with organic anion transporters.
Journal: Journal of pharmacological sciences
Published: December 16, 2020
Protein kinase C activation upregulates human L-type amino acid transporter 2 function.
Journal: The journal of physiological sciences : JPS
Published: October 13, 2020
JPH203, a newly developed anti-cancer drug, shows a preincubation inhibitory effect on L-type amino acid transporter 1 function.
Journal: Journal of pharmacological sciences
Published: February 25, 2019
Last Updated: 09/26/2026