Hanan S. Althagafy

Jeddah, 21589, Saudi Arabia

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 37 publications

The angiotensin II receptor blocker candesartan mitigates cisplatin-induced myocardial injury via suppression of TLR-4/NF-κB/IRF-3/AP-1 signaling and restoration of antioxidant defenses.

The angiotensin II receptor blocker candesartan mitigates cisplatin-induced myocardial injury via suppression of TLR-4/NF-κB/IRF-3/AP-1 signaling and restoration of antioxidant defenses.

Journal: Tissue & cell

Published: January 26, 2026

Nifuroxazide attenuates bisphenol A-induced male reproductive toxicity by modulating oxidative stress, inflammation, and Nrf2/HO-1 and necroptosis pathways.

Nifuroxazide attenuates bisphenol A-induced male reproductive toxicity by modulating oxidative stress, inflammation, and Nrf2/HO-1 and necroptosis pathways.

Journal: Tissue & cell

Published: September 02, 2025

The protective effect of ambroxol against cyclophosphamide-induced acute kidney injury involves Nrf2/HO-1 signaling upregulation and suppression of oxidative and inflammatory damage.

The protective effect of ambroxol against cyclophosphamide-induced acute kidney injury involves Nrf2/HO-1 signaling upregulation and suppression of oxidative and inflammatory damage.

Journal: Naunyn-Schmiedeberg's archives of pharmacology

Published: August 14, 2025

Candesartan preserves aortic structure and function in cisplatin-treated rats by upregulating SIRT1/Nrf2/HO-1 signaling and suppressing oxidative stress, TLR-4/NF-κB signaling, and necroptosis.

Candesartan preserves aortic structure and function in cisplatin-treated rats by upregulating SIRT1/Nrf2/HO-1 signaling and suppressing oxidative stress, TLR-4/NF-κB signaling, and necroptosis.

Journal: Frontiers in pharmacology

Published: August 03, 2025

Renoprotective effect of diosmin against chlorpyrifos-induced kidney injury is mediated by the regulation of TLR4/HMGB1/NF-κB, PPAR-γ/SIRT1, and Bax/Bcl2 signals.

Renoprotective effect of diosmin against chlorpyrifos-induced kidney injury is mediated by the regulation of TLR4/HMGB1/NF-κB, PPAR-γ/SIRT1, and Bax/Bcl2 signals.

Journal: Journal of molecular histology

Published: June 08, 2025

Protective effect of ambroxol on cyclophosphamide-induced intestinal damage: involvement of oxidative stress, inflammation, and Keap-1/Nrf2/HO-1 signaling.

Protective effect of ambroxol on cyclophosphamide-induced intestinal damage: involvement of oxidative stress, inflammation, and Keap-1/Nrf2/HO-1 signaling.

Journal: Journal of molecular histology

Published: May 26, 2025

Modulation of NF-κB/NLRP3 inflammasome axis, Nrf2/HO-1 signaling and attenuation of oxidative stress mediate the protective effect of ambroxol against cyclophosphamide cardiotoxicity.

Modulation of NF-κB/NLRP3 inflammasome axis, Nrf2/HO-1 signaling and attenuation of oxidative stress mediate the protective effect of ambroxol against cyclophosphamide cardiotoxicity.

Journal: Biochemical and biophysical research communications

Published: April 17, 2025

Attenuation of NF-κB/NLRP3 inflammasome axis and oxidative stress, and upregulation of Nrf2/HO-1 signaling mediate the protective effect of S-carboxymethylcysteine against cyclophosphamide-induced cardiotoxicity.

Attenuation of NF-κB/NLRP3 inflammasome axis and oxidative stress, and upregulation of Nrf2/HO-1 signaling mediate the protective effect of S-carboxymethylcysteine against cyclophosphamide-induced cardiotoxicity.

Journal: Tissue & cell

Published: April 10, 2025

Ambroxol mitigates cyclophosphamide-induced liver injury by suppressing TLR-4/NF-κB signaling and oxidative stress and upregulating cytoglobin, TXNRD1 and HMGB1.

Ambroxol mitigates cyclophosphamide-induced liver injury by suppressing TLR-4/NF-κB signaling and oxidative stress and upregulating cytoglobin, TXNRD1 and HMGB1.

Journal: World journal of gastroenterology

Published: April 07, 2025

Harnessing GSK-3β inhibition for lung cancer therapy: emerging opportunities and challenges.

Harnessing GSK-3β inhibition for lung cancer therapy: emerging opportunities and challenges.

Journal: Medical oncology (Northwood, London, England)

Published: February 14, 2025

Umbelliferone reverses neuronal damage induced by chronic Chlorpyrifos exposure via suppressing NF-κB/STAT3/NLRP3 and boosting Keap-1/Nrf2/HO-1 signals.

Umbelliferone reverses neuronal damage induced by chronic Chlorpyrifos exposure via suppressing NF-κB/STAT3/NLRP3 and boosting Keap-1/Nrf2/HO-1 signals.

Journal: Metabolic brain disease

Published: January 30, 2025

The role of Wnt/β-catenin signaling in lung cancer progression and therapy: a comprehensive review.

The role of Wnt/β-catenin signaling in lung cancer progression and therapy: a comprehensive review.

Journal: Medical oncology (Northwood, London, England)

Published: December 20, 2024

Showing 1-12 of 37

Last Updated: 09/26/2026