Hanna P. Lesch

Kuopio, Finland

Last Updated: 09/26/2026

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Found 24 publications

Novel, Stable, and Well-Secreted Single-Chain Fc Forms of Programmed Death-1 Immune Checkpoint Inhibitor Efficiently Block PD-1/PD-L1 Interaction.

Novel, Stable, and Well-Secreted Single-Chain Fc Forms of Programmed Death-1 Immune Checkpoint Inhibitor Efficiently Block PD-1/PD-L1 Interaction.

Journal: Human gene therapy

Published: February 12, 2026

The co-delivery of Programmed Death 1 ligands enhances and prolongs rAAV-mediated gene expression in pre-immunized mice.

The co-delivery of Programmed Death 1 ligands enhances and prolongs rAAV-mediated gene expression in pre-immunized mice.

Journal: Gene therapy

Published: June 25, 2025

Optimizing lentiviral vector formulation conditions for efficient ex vivo transduction of primary human T cells in chimeric antigen receptor T-cell manufacturing.

Optimizing lentiviral vector formulation conditions for efficient ex vivo transduction of primary human T cells in chimeric antigen receptor T-cell manufacturing.

Journal: Cytotherapy

Published: November 15, 2023

Corrigendum: Optimized riboswitch-regulated AAV vector for VEGF-B gene therapy.

Corrigendum: Optimized riboswitch-regulated AAV vector for VEGF-B gene therapy.

Journal: Frontiers in medicine

Published: January 13, 2023

Optimized riboswitch-regulated AAV vector for VEGF-B gene therapy.

Optimized riboswitch-regulated AAV vector for VEGF-B gene therapy.

Journal: Frontiers in medicine

Published: September 23, 2022

Functional roles of the membrane-associated AAV protein MAAP.

Functional roles of the membrane-associated AAV protein MAAP.

Journal: Scientific reports

Published: March 29, 2021

Experimental Evaluation of an Interferometric Light Microscopy Particle Counter for Titering and Characterization of Virus Preparations.

Experimental Evaluation of an Interferometric Light Microscopy Particle Counter for Titering and Characterization of Virus Preparations.

Journal: Viruses

Published: March 28, 2021

Evaluation of the Single-Use Fixed-Bed Bioreactors in Scalable Virus Production.

Evaluation of the Single-Use Fixed-Bed Bioreactors in Scalable Virus Production.

Journal: Biotechnology journal

Published: May 13, 2020

Development of Large-Scale Downstream Processing for Lentiviral Vectors.

Development of Large-Scale Downstream Processing for Lentiviral Vectors.

Journal: Molecular therapy. Methods & clinical development

Published: March 04, 2020

Benchmarking of Scale-X Bioreactor System in Lentiviral and Adenoviral Vector Production.

Benchmarking of Scale-X Bioreactor System in Lentiviral and Adenoviral Vector Production.

Journal: Human gene therapy

Published: February 21, 2020

Detection of lentiviral suicide gene therapy in C6 rat glioma using hyperpolarised [1-13 C]pyruvate.

Detection of lentiviral suicide gene therapy in C6 rat glioma using hyperpolarised [1-13 C]pyruvate.

Journal: NMR in biomedicine

Published: July 23, 2019

Preclinical Proof-of-Concept, Analytical Development, and Commercial Scale Production of Lentiviral Vector in Adherent Cells.

Preclinical Proof-of-Concept, Analytical Development, and Commercial Scale Production of Lentiviral Vector in Adherent Cells.

Journal: Molecular therapy. Methods & clinical development

Published: May 14, 2019

Showing 1-12 of 24

Last Updated: 09/26/2026