Hanno Schieferstein
Frankfurter Str. 250
64293, Germany
64293, Germany
Last Updated: 09/26/2026
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Found 24 publications
Identification, structural elucidation and nonclinical characterisation of oxMET1: a further major metabolite of xevinapant?
Journal: Xenobiotica; the fate of foreign compounds in biological systems
Published: February 16, 2026
Structure Elucidation and Initial Characterization of a N-glucuronide Metabolite (M1) of Tuvusertib.
Structure Elucidation and Initial Characterization of a N-glucuronide Metabolite (M1) of Tuvusertib.
Journal: European journal of drug metabolism and pharmacokinetics
Published: January 15, 2026
Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends.
Journal: Clinical pharmacology and therapeutics
Published: December 12, 2025
An Integrated Nonclinical and Clinical Risk Assessment of the Effects of Investigational ATRi Tuvusertib on QTc Interval in Patients With Solid Tumors.
Journal: Clinical and translational science
Published: September 04, 2025
Development and in vivo evaluation of 18F-labeled PET tracers covalently targeting KRAS-G12C for noninvasive cancer diagnosis and therapy monitoring.
Journal: Theranostics
Published: August 14, 2025
Guided Sample Pooling in Human Mass Balance Studies: A Recommended Strategic Decision Framework.
Journal: Clinical pharmacology and therapeutics
Published: June 26, 2025
Microtracer-Based Assessment of the Mass Balance, Pharmacokinetics, and Excretion of [14C]Berzosertib, an Intravenous ATR Inhibitor, in Patients With Advanced Solid Tumors: A Phase 1 Study.
Journal: Clinical pharmacology in drug development
Published: February 13, 2025
M4205 (IDRX-42) Is a Highly Selective and Potent Inhibitor of Relevant Oncogenic Driver and Resistance Variants of KIT in Cancer.
Journal: Molecular cancer therapeutics
Published: August 15, 2024
Imaging GRPr Expression in Metastatic Castration-Resistant Prostate Cancer with [68Ga]Ga-RM2-A Head-to-Head Pilot Comparison with [68Ga]Ga-PSMA-11.
Journal: Cancers
Published: November 08, 2023
Evobrutinib pathway to its major metabolite M463-2 and insights from a biotransformation and DDI perspective.
Journal: Xenobiotica; the fate of foreign compounds in biological systems
Published: October 26, 2023
Recommendations on the Use of Multiple Labels in Human Mass Balance Studies.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: September 18, 2023
Non-Labeled, Stable Labeled, or Radiolabelled Approaches for Provision of Intravenous Pharmacokinetics in Humans: A Discussion Piece.
Journal: Clinical pharmacology and therapeutics
Published: August 21, 2023
Last Updated: 09/26/2026