Hans-wolfgang W. Klafki

Von Siebold Str. 5
Goettingen, NI 37075, Germany

Last Updated: 09/26/2026

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Found 28 publications

Amyloid Plaques Ameliorate Memory Deficits and Hippocampal Neuron Loss in an Aβ4-42-Driven Alzheimer's Disease Mouse Model.

Amyloid Plaques Ameliorate Memory Deficits and Hippocampal Neuron Loss in an Aβ4-42-Driven Alzheimer's Disease Mouse Model.

Journal: Molecular neurobiology

Published: February 27, 2026

Evaluation of fully automated ApoE4 proteotyping for APOE ε4 genotype estimation in the FINDERI cohort.

Evaluation of fully automated ApoE4 proteotyping for APOE ε4 genotype estimation in the FINDERI cohort.

Journal: Alzheimer's & dementia (Amsterdam, Netherlands)

Published: February 23, 2026

Aggregation-dependent epitope sequence and modification fingerprints of anti-Aβ antibodies.

Aggregation-dependent epitope sequence and modification fingerprints of anti-Aβ antibodies.

Journal: eLife

Published: February 09, 2026

Evaluation of a fully automated assay for the measurement of plasma pTau217 and a composite score integrating the ratio Aβ1-42/1-40 as biomarkers of Alzheimer's disease.

Evaluation of a fully automated assay for the measurement of plasma pTau217 and a composite score integrating the ratio Aβ1-42/1-40 as biomarkers of Alzheimer's disease.

Journal: European archives of psychiatry and clinical neuroscience

Published: December 02, 2024

Phosphorylated tau 181 and 217 are elevated in serum and muscle of patients with amyotrophic lateral sclerosis.

Phosphorylated tau 181 and 217 are elevated in serum and muscle of patients with amyotrophic lateral sclerosis.

Journal: Nature communications

Published: August 31, 2024

Amino-terminally elongated Aβ peptides are generated by the secreted metalloprotease ADAMTS4 and deposit in a subset of Alzheimer's disease brains.

Amino-terminally elongated Aβ peptides are generated by the secreted metalloprotease ADAMTS4 and deposit in a subset of Alzheimer's disease brains.

Journal: Neuropathology and applied neurobiology

Published: April 08, 2024

Assessment of immunoprecipitation with subsequent immunoassays for the blood-based diagnosis of Alzheimer's disease.

Assessment of immunoprecipitation with subsequent immunoassays for the blood-based diagnosis of Alzheimer's disease.

Journal: European archives of psychiatry and clinical neuroscience

Published: October 10, 2023

Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer's disease model mice.

Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer's disease model mice.

Journal: Nature neuroscience

Published: September 28, 2023

Blood plasma biomarkers for Alzheimer's disease: Aβ1-42/1-40 vs. AβX-42/X-40.

Blood plasma biomarkers for Alzheimer's disease: Aβ1-42/1-40 vs. AβX-42/X-40.

Journal: Clinical chemistry and laboratory medicine

Published: September 07, 2023

Brain Region-Specific Differences in Amyloid-β Plaque Composition in 5XFAD Mice.

Brain Region-Specific Differences in Amyloid-β Plaque Composition in 5XFAD Mice.

Journal: Life (Basel, Switzerland)

Published: March 16, 2023

Matrix Development for the Detection of Phosphorylated Amyloid-β Peptides by MALDI-TOF-MS.

Matrix Development for the Detection of Phosphorylated Amyloid-β Peptides by MALDI-TOF-MS.

Journal: Journal of the American Society for Mass Spectrometry

Published: January 27, 2023

A Combination of Caffeine Supplementation and Enriched Environment in an Alzheimer's Disease Mouse Model.

A Combination of Caffeine Supplementation and Enriched Environment in an Alzheimer's Disease Mouse Model.

Journal: International journal of molecular sciences

Published: December 21, 2022

Showing 1-12 of 28

Last Updated: 09/26/2026