Haoche X. Wei

No.16, Renmin Nan Road
Chengdu, 610041, China

Last Updated: 09/26/2026

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Found 19 publications

Identification and Optimization of Pyridone Derivatives as Pan-MEK/RAF Nondegrading Molecular Glues for the Treatment of RAS-Driven Cancers.

Identification and Optimization of Pyridone Derivatives as Pan-MEK/RAF Nondegrading Molecular Glues for the Treatment of RAS-Driven Cancers.

Journal: Journal of medicinal chemistry

Published: May 07, 2026

CMD-OPT model enables the discovery of a potent and selective RIPK2 inhibitor as preclinical candidate for the treatment of acute liver injury.

CMD-OPT model enables the discovery of a potent and selective RIPK2 inhibitor as preclinical candidate for the treatment of acute liver injury.

Journal: Acta pharmaceutica Sinica. B

Published: October 30, 2024

The cytotoxic natural compound erianin binds to colchicine site of β-tubulin and overcomes taxane resistance.

The cytotoxic natural compound erianin binds to colchicine site of β-tubulin and overcomes taxane resistance.

Journal: Bioorganic chemistry

Published: March 26, 2024

Postauricular hairline plus temporal approach gasless full-endoscopic parotidectomy for tumors in deep lobe of parotid gland: a 16-case report

Postauricular hairline plus temporal approach gasless full-endoscopic parotidectomy for tumors in deep lobe of parotid gland: a 16-case report

Journal: Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology

Published: January 27, 2024

Discovery of Potent and Selective Phosphatidylinositol 3-Phosphate 5-Kinase (PIKfyve) Inhibitors as Methuosis Inducers.

Discovery of Potent and Selective Phosphatidylinositol 3-Phosphate 5-Kinase (PIKfyve) Inhibitors as Methuosis Inducers.

Journal: Journal of medicinal chemistry

Published: December 20, 2023

Identification of abemaciclib derivatives targeting cyclin-dependent kinase 4 and 6 using molecular dynamics, binding free energy calculation, synthesis, and pharmacological evaluation.

Identification of abemaciclib derivatives targeting cyclin-dependent kinase 4 and 6 using molecular dynamics, binding free energy calculation, synthesis, and pharmacological evaluation.

Journal: Frontiers in pharmacology

Published: February 13, 2023

Novel organoid construction strategy for non-involuting congenital hemangioma for drug validation.

Novel organoid construction strategy for non-involuting congenital hemangioma for drug validation.

Journal: Journal of biological engineering

Published: January 18, 2023

Interactions between curcumin and human salt-induced kinase 3 elucidated from computational tools and experimental methods.

Interactions between curcumin and human salt-induced kinase 3 elucidated from computational tools and experimental methods.

Journal: Frontiers in pharmacology

Published: December 12, 2022

Discovery of pyrimidine-5-carboxamide derivatives as novel salt-inducible kinases (SIKs) inhibitors for inflammatory bowel disease (IBD) treatment.

Discovery of pyrimidine-5-carboxamide derivatives as novel salt-inducible kinases (SIKs) inhibitors for inflammatory bowel disease (IBD) treatment.

Journal: European journal of medicinal chemistry

Published: December 05, 2022

Small Molecules Promote Selective Denaturation and Degradation of Tubulin Heterodimers through a Low-Barrier Hydrogen Bond.

Small Molecules Promote Selective Denaturation and Degradation of Tubulin Heterodimers through a Low-Barrier Hydrogen Bond.

Journal: Journal of medicinal chemistry

Published: June 28, 2022

Cevipabulin-tubulin complex reveals a novel agent binding site on α-tubulin with tubulin degradation effect.

Cevipabulin-tubulin complex reveals a novel agent binding site on α-tubulin with tubulin degradation effect.

Journal: Science advances

Published: January 05, 2021

Chlorophyllin Modulates Gut Microbiota and Inhibits Intestinal Inflammation to Ameliorate Hepatic Fibrosis in Mice.

Chlorophyllin Modulates Gut Microbiota and Inhibits Intestinal Inflammation to Ameliorate Hepatic Fibrosis in Mice.

Journal: Frontiers in physiology

Published: May 27, 2018

Showing 1-12 of 19

Last Updated: 09/26/2026