Haoliang Yuan

Jiangsu Key Laboratory Of Drug Discovery For Metabolic Disease, State Key Laboratory Of Natural Medicines
Nanjing, 210009, China

Last Updated: 09/26/2026

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Found 53 publications

Design, synthesis, and biological evaluation of aryl urea derivatives as novel STING inhibitors based on SN-011.

Design, synthesis, and biological evaluation of aryl urea derivatives as novel STING inhibitors based on SN-011.

Journal: Bioorganic & medicinal chemistry

Published: May 25, 2026

Design, Synthesis, and Biological Evaluation of Arylimidazole Derivatives as Potent PPARδ Agonists for the Treatment of Renal Fibrosis.

Design, Synthesis, and Biological Evaluation of Arylimidazole Derivatives as Potent PPARδ Agonists for the Treatment of Renal Fibrosis.

Journal: Journal of medicinal chemistry

Published: February 10, 2026

Visible-Light-Mediated Cascade Construction of Polysubstituted Naphthalene Scaffolds from 2-Methylbenzophenones and (Trifluoromethyl)alkenes.

Visible-Light-Mediated Cascade Construction of Polysubstituted Naphthalene Scaffolds from 2-Methylbenzophenones and (Trifluoromethyl)alkenes.

Journal: Organic letters

Published: October 05, 2025

Discovery of indane and naphthalene derivatives as USP7 inhibitors.

Discovery of indane and naphthalene derivatives as USP7 inhibitors.

Journal: European journal of medicinal chemistry

Published: April 24, 2025

Design, synthesis, and Biological evaluation of novel macrocyclic derivatives as potent ATP-citrate lyase inhibitors.

Design, synthesis, and Biological evaluation of novel macrocyclic derivatives as potent ATP-citrate lyase inhibitors.

Journal: European journal of medicinal chemistry

Published: February 28, 2025

Discovery of an Orally Bioavailable STING Inhibitor with In Vivo Anti-Inflammatory Activity in Mice with STING-Mediated Inflammation.

Discovery of an Orally Bioavailable STING Inhibitor with In Vivo Anti-Inflammatory Activity in Mice with STING-Mediated Inflammation.

Journal: Journal of medicinal chemistry

Published: January 28, 2025

Design, Synthesis, and Biological Evaluation of Chroman Derivatives as PD-1/PD-L1 Antagonists.

Design, Synthesis, and Biological Evaluation of Chroman Derivatives as PD-1/PD-L1 Antagonists.

Journal: Journal of chemical information and modeling

Published: June 10, 2024

PIII/PV-Catalyzed Beckmann Reaction and Sequential [2,3]-Sigmatropic Rearrangement to Construct 2-Amidopyridines.

PIII/PV-Catalyzed Beckmann Reaction and Sequential [2,3]-Sigmatropic Rearrangement to Construct 2-Amidopyridines.

Journal: Organic letters

Published: April 29, 2024

V-domain immunoglobulin suppressor of T-cell activation and programmed death receptor 1 dual checkpoint blockade enhances antitumour immunity and survival in glioblastoma.

V-domain immunoglobulin suppressor of T-cell activation and programmed death receptor 1 dual checkpoint blockade enhances antitumour immunity and survival in glioblastoma.

Journal: British journal of pharmacology

Published: April 23, 2024

Design, synthesis, and biological evaluation of piperazine derivatives as pan-PPARs agonists for the treatment of liver fibrosis.

Design, synthesis, and biological evaluation of piperazine derivatives as pan-PPARs agonists for the treatment of liver fibrosis.

Journal: European journal of medicinal chemistry

Published: February 20, 2024

Discovery and Structural Optimization of Novel Quinolone Derivatives as Potent Irreversible Pan-Fibroblast Growth Factor Receptor Inhibitors for Treating Solid Tumors.

Discovery and Structural Optimization of Novel Quinolone Derivatives as Potent Irreversible Pan-Fibroblast Growth Factor Receptor Inhibitors for Treating Solid Tumors.

Journal: Journal of medicinal chemistry

Published: June 19, 2023

Discovery of the First Subnanomolar PPARα/δ Dual Agonist for the Treatment of Cholestatic Liver Diseases.

Discovery of the First Subnanomolar PPARα/δ Dual Agonist for the Treatment of Cholestatic Liver Diseases.

Journal: Journal of medicinal chemistry

Published: May 27, 2023

Showing 1-12 of 53

Last Updated: 09/26/2026