Haoyu Zhang

Key Laboratory Of Structure Based Drug Design And Discovery, 103 Wenhua Road, Shenhe District
Shenyang, 110016, China

Last Updated: 09/26/2026

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Found 14 publications

Design, Synthesis, Biological Activity Evaluation, and Molecular Docking of 2-Aminopyrimidine-Based PKMYT1 Inhibitors.

Design, Synthesis, Biological Activity Evaluation, and Molecular Docking of 2-Aminopyrimidine-Based PKMYT1 Inhibitors.

Journal: Biomedicines
Published: August 05, 2026

Design, Synthesis, and Biological Activity Evaluation of Quinazoline-Based PLK4 Inhibitors.

Design, Synthesis, and Biological Activity Evaluation of Quinazoline-Based PLK4 Inhibitors.

Journal: Biomedicines
Published: June 08, 2026

Discovery of highly selective and potent CYP1B1 inhibitors for overcoming paclitaxel resistance in A549/Taxol cells.

Discovery of highly selective and potent CYP1B1 inhibitors for overcoming paclitaxel resistance in A549/Taxol cells.

Journal: European journal of medicinal chemistry
Published: May 19, 2026

Design, Synthesis, and Computational Insights into PKMYT1 Inhibitors for the Treatment of Breast Cancer.

Design, Synthesis, and Computational Insights into PKMYT1 Inhibitors for the Treatment of Breast Cancer.

Journal: Biomedicines
Published: July 20, 2025

Discovery of Highly Selective CYP1B1 Inhibitors.

Discovery of Highly Selective CYP1B1 Inhibitors.

Journal: Journal of medicinal chemistry
Published: June 16, 2025

Design, Synthesis, and Biological Activity Evaluation of Deuterated Diphenyl Azole Alcohol-Based CYP51 Inhibitors.

Design, Synthesis, and Biological Activity Evaluation of Deuterated Diphenyl Azole Alcohol-Based CYP51 Inhibitors.

Journal: Journal of medicinal chemistry
Published: June 03, 2025

Design, synthesis, and activity evaluation of novel tetrazole-based CYP51 inhibitors.

Design, synthesis, and activity evaluation of novel tetrazole-based CYP51 inhibitors.

Journal: Bioorganic chemistry
Published: May 09, 2025

Rational design of CZL-S092: A novel indazole-based PLK4 inhibitor targeting neuroblastoma through virtual screening and fragment-based drug design strategies.

Rational design of CZL-S092: A novel indazole-based PLK4 inhibitor targeting neuroblastoma through virtual screening and fragment-based drug design strategies.

Journal: European journal of medicinal chemistry
Published: April 27, 2025

Discovery of highly potent triazole derivatives with broad-spectrum antifungal activity based on Iodiconazole.

Discovery of highly potent triazole derivatives with broad-spectrum antifungal activity based on Iodiconazole.

Journal: European journal of medicinal chemistry
Published: July 24, 2024

Design, synthesis and bioactivity evaluation of triazole antifungal drugs with phenylthiophene structure.

Design, synthesis and bioactivity evaluation of triazole antifungal drugs with phenylthiophene structure.

Journal: Bioorganic chemistry
Published: June 25, 2024

Insights into the selective mechanism of PDE2/9a inhibitors from silico aspects.

Insights into the selective mechanism of PDE2/9a inhibitors from silico aspects.

Journal: Journal of biomolecular structure & dynamics
Published: March 25, 2024

Discovery of non-sulfonamide carbonic anhydrase IX inhibitors through structure-based virtual screening.

Discovery of non-sulfonamide carbonic anhydrase IX inhibitors through structure-based virtual screening.

Journal: Physical chemistry chemical physics : PCCP
Published: February 29, 2024
Showing 1-12 of 14

Last Updated: 09/26/2026