Harri M. Itkonen

Norway

Last Updated: 09/26/2026

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Found 34 publications

Castration-resistant prostate cancer cells are addicted to the high activity of cyclin-dependent kinase 2.

Castration-resistant prostate cancer cells are addicted to the high activity of cyclin-dependent kinase 2.

Journal: Molecular oncology

Published: March 31, 2026

CDK12/13 Inhibition Induces DNA Hypomethylation and Sensitizes Cancer Cells to Compounds Targeting DNA-PK.

CDK12/13 Inhibition Induces DNA Hypomethylation and Sensitizes Cancer Cells to Compounds Targeting DNA-PK.

Journal: Journal of cellular and molecular medicine

Published: March 24, 2026

Inhibition of RNA polymerase II-activating CDK9 and CDK12/13, but not of cell cycle relevant CDKs, induces apoptosis by downregulating the short-lived Bcl-2 proteins Mcl1 and Bfl1/A1.

Inhibition of RNA polymerase II-activating CDK9 and CDK12/13, but not of cell cycle relevant CDKs, induces apoptosis by downregulating the short-lived Bcl-2 proteins Mcl1 and Bfl1/A1.

Journal: Cell death & disease

Published: January 09, 2026

Inactivation of CDK12 Enhances Mitochondrial Efficiency to Suppress DNA Damage.

Inactivation of CDK12 Enhances Mitochondrial Efficiency to Suppress DNA Damage.

Journal: Journal of cellular and molecular medicine

Published: September 14, 2025

Dynamic O-GlcNAcylation and phosphorylation attract and expel proteins from RNA polymerase II to regulate mRNA maturation.

Dynamic O-GlcNAcylation and phosphorylation attract and expel proteins from RNA polymerase II to regulate mRNA maturation.

Journal: Journal of biomedical science

Published: December 10, 2024

Altered behaviour and immune response in mice with NHLRC2 p.Asp148Tyr variant.

Altered behaviour and immune response in mice with NHLRC2 p.Asp148Tyr variant.

Journal: Brain, behavior, & immunity - health

Published: September 16, 2024

Emerging frontiers in androgen receptor research for prostate Cancer: insights from the 2nd international androgen receptor Symposium.

Emerging frontiers in androgen receptor research for prostate Cancer: insights from the 2nd international androgen receptor Symposium.

Journal: Journal of experimental & clinical cancer research : CR

Published: June 15, 2024

Compromised CDK12 activity causes dependency on the high activity of O-GlcNAc transferase.

Compromised CDK12 activity causes dependency on the high activity of O-GlcNAc transferase.

Journal: Glycobiology

Published: April 01, 2024

CDK12-inactivation-induced MYC signaling causes dependency on the splicing kinase SRPK1.

CDK12-inactivation-induced MYC signaling causes dependency on the splicing kinase SRPK1.

Journal: Molecular oncology

Published: October 11, 2023

Revealing the History and Mystery of RNA-Seq.

Revealing the History and Mystery of RNA-Seq.

Journal: Current issues in molecular biology

Published: January 23, 2023

Castration-resistant prostate cancer cells are dependent on the high activity of CDK7.

Castration-resistant prostate cancer cells are dependent on the high activity of CDK7.

Journal: Journal of cancer research and clinical oncology

Published: September 04, 2022

O-GlcNAc transferase maintains metabolic homeostasis in response to CDK9 inhibition.

O-GlcNAc transferase maintains metabolic homeostasis in response to CDK9 inhibition.

Journal: Glycobiology

Published: April 11, 2022

Showing 1-12 of 34

Last Updated: 09/26/2026