Hartmut G. Ruetten

R&d
Frankfurt Am Main, HE 65926, Germany

Last Updated: 09/26/2026

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Found 56 publications

A biological-systems-based analysis using proteomic and metabolic network inference reveals mechanistic insights into hepatic steatosis.

A biological-systems-based analysis using proteomic and metabolic network inference reveals mechanistic insights into hepatic steatosis.

Journal: Metabolism: clinical and experimental

Published: June 30, 2025

A biological-systems-based analysis using proteomic and metabolic network inference reveals mechanistic insights into hepatic steatosis.

A biological-systems-based analysis using proteomic and metabolic network inference reveals mechanistic insights into hepatic steatosis.

Journal: Metabolism: clinical and experimental

Published: June 30, 2025

A Biological-Systems-Based Analyses Using Proteomic and Metabolic Network Inference Reveals Mechanistic Insights into Hepatic Lipid Accumulation: An IMI-DIRECT Study.

A Biological-Systems-Based Analyses Using Proteomic and Metabolic Network Inference Reveals Mechanistic Insights into Hepatic Lipid Accumulation: An IMI-DIRECT Study.

Journal: medRxiv : the preprint server for health sciences

Published: June 12, 2025

Bayesian network imputation methods applied to multi-omics data identify putative causal relationships in a type 2 diabetes dataset containing incomplete data: An IMI DIRECT Study.

Bayesian network imputation methods applied to multi-omics data identify putative causal relationships in a type 2 diabetes dataset containing incomplete data: An IMI DIRECT Study.

Journal: PLoS genetics

Published: February 20, 2025

The dynamics of the gut microbiota in prediabetes during a four-year follow-up among European patients-an IMI-DIRECT prospective study.

The dynamics of the gut microbiota in prediabetes during a four-year follow-up among European patients-an IMI-DIRECT prospective study.

Journal: Genome medicine

Published: December 22, 2024

Hormonal regulation of human adipose tissue lipolysis: impact of adipose GIP system in overweight and obesity.

Hormonal regulation of human adipose tissue lipolysis: impact of adipose GIP system in overweight and obesity.

Journal: European journal of endocrinology

Published: July 16, 2024

Role of human plasma metabolites in prediabetes and type 2 diabetes from the IMI-DIRECT study.

Role of human plasma metabolites in prediabetes and type 2 diabetes from the IMI-DIRECT study.

Journal: Diabetologia

Published: February 28, 2024

The Association of Cardiometabolic, Diet and Lifestyle Parameters With Plasma Glucagon-like Peptide-1: An IMI DIRECT Study.

The Association of Cardiometabolic, Diet and Lifestyle Parameters With Plasma Glucagon-like Peptide-1: An IMI DIRECT Study.

Journal: The Journal of clinical endocrinology and metabolism

Published: August 11, 2023

Author Correction: Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models.

Author Correction: Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models.

Journal: Nature biotechnology

Published: May 02, 2023

Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models.

Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models.

Journal: Nature biotechnology

Published: March 15, 2022

Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials.

Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials.

Journal: The lancet. Diabetes & endocrinology

Published: February 25, 2022

The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits.

The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits.

Journal: Cell metabolism

Published: February 03, 2022

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Last Updated: 09/26/2026