Hayley L. Whitfield

Norwich Research Park
Norwich, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 20 publications

The Diphosphoinositol Polyphosphate Phosphohydrolase 1 family binds IP8 in catalytically-productive twist-boat and chair conformations and associates in a ligand-dependent manner.

The Diphosphoinositol Polyphosphate Phosphohydrolase 1 family binds IP8 in catalytically-productive twist-boat and chair conformations and associates in a ligand-dependent manner.

Journal: International journal of biological macromolecules

Published: December 18, 2025

Analysis of Inositol Phosphates, Diphosphoinositol Phosphates, and Their Analogs by HPLC on an Acid-Compatible Stationary Phase with Detection by Complexation with Ferric Ion.

Analysis of Inositol Phosphates, Diphosphoinositol Phosphates, and Their Analogs by HPLC on an Acid-Compatible Stationary Phase with Detection by Complexation with Ferric Ion.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: August 29, 2025

A minimum catalytic unit for synthesis of InsP6 and 5-PP-InsP5 in Arabidopsis.

A minimum catalytic unit for synthesis of InsP6 and 5-PP-InsP5 in Arabidopsis.

Journal: The Biochemical journal

Published: April 16, 2025

Phosphorus-specific, liquid chromatography inductively coupled plasma mass spectrometry for analysis of inositol phosphate and inositol pyrophosphate metabolism.

Phosphorus-specific, liquid chromatography inductively coupled plasma mass spectrometry for analysis of inositol phosphate and inositol pyrophosphate metabolism.

Journal: The Biochemical journal

Published: April 11, 2025

The intracellular inositol (pyro)phosphate receptor AtSPX1 reciprocally binds to P1BS DNA.

The intracellular inositol (pyro)phosphate receptor AtSPX1 reciprocally binds to P1BS DNA.

Journal: Nature communications

Published: January 28, 2025

Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 (StITPK1).

Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 (StITPK1).

Journal: Biochemistry

Published: December 26, 2023

Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity.

Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity.

Journal: Nature communications

Published: August 19, 2023

Diversification in the inositol tris/tetrakisphosphate kinase (ITPK) family: crystal structure and enzymology of the outlier AtITPK4.

Diversification in the inositol tris/tetrakisphosphate kinase (ITPK) family: crystal structure and enzymology of the outlier AtITPK4.

Journal: The Biochemical journal

Published: December 01, 2022

Characterisation of a soil MINPP phytase with remarkable long-term stability and activity from Acinetobacter sp.

Characterisation of a soil MINPP phytase with remarkable long-term stability and activity from Acinetobacter sp.

Journal: PloS one

Published: March 08, 2022

Phytase dose-dependent response of kidney inositol phosphate levels in poultry.

Phytase dose-dependent response of kidney inositol phosphate levels in poultry.

Journal: PloS one

Published: February 16, 2022

Allosteric Site on SHIP2 Identified Through Fluorescent Ligand Screening and Crystallography: A Potential New Target for Intervention.

Allosteric Site on SHIP2 Identified Through Fluorescent Ligand Screening and Crystallography: A Potential New Target for Intervention.

Journal: Journal of medicinal chemistry

Published: March 16, 2021

An ATP-responsive metabolic cassette comprised of inositol tris/tetrakisphosphate kinase 1 (ITPK1) and inositol pentakisphosphate 2-kinase (IPK1) buffers diphosphosphoinositol phosphate levels.

An ATP-responsive metabolic cassette comprised of inositol tris/tetrakisphosphate kinase 1 (ITPK1) and inositol pentakisphosphate 2-kinase (IPK1) buffers diphosphosphoinositol phosphate levels.

Journal: The Biochemical journal

Published: May 21, 2020

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Last Updated: 09/26/2026