Hayoung Hwang

Daegu, Republic of Korea

Last Updated: 09/26/2026

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Found 27 publications

Synthesis of 3-desoxycollinoketone B and its ability to reduce Alzheimer-associated misfolded proteins.

Synthesis of 3-desoxycollinoketone B and its ability to reduce Alzheimer-associated misfolded proteins.

Journal: Nature communications

Published: February 24, 2025

Discovery of the therapeutic potential of PPARδ agonist bearing 1,3,4- thiadiazole in inflammatory disorders.

Discovery of the therapeutic potential of PPARδ agonist bearing 1,3,4- thiadiazole in inflammatory disorders.

Journal: European journal of medicinal chemistry

Published: July 02, 2024

Highly potent and selective PPARδ agonist reverses memory deficits in mouse models of Alzheimer's disease.

Highly potent and selective PPARδ agonist reverses memory deficits in mouse models of Alzheimer's disease.

Journal: Theranostics

Published: March 28, 2024

Engineering small-molecule analogues of altiratinib via CREB-regulated transcription co-activator 3-target screening for the development of potent and safe topical therapeutics against skin hyperpigmentary diseases.

Engineering small-molecule analogues of altiratinib via CREB-regulated transcription co-activator 3-target screening for the development of potent and safe topical therapeutics against skin hyperpigmentary diseases.

Journal: Clinical and translational medicine

Published: October 11, 2023

Exploration of Tetrahydroisoquinoline- and Benzo[c]azepine-Based Sphingosine 1-Phosphate Receptor 1 Agonists for the Treatment of Multiple Sclerosis.

Exploration of Tetrahydroisoquinoline- and Benzo[c]azepine-Based Sphingosine 1-Phosphate Receptor 1 Agonists for the Treatment of Multiple Sclerosis.

Journal: Journal of medicinal chemistry

Published: July 25, 2023

Discovery of Novel Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis.

Discovery of Novel Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis.

Journal: Journal of medicinal chemistry

Published: January 25, 2022

Estrogen-Related Receptor γ Maintains Pancreatic Acinar Cell Function and Identity by Regulating Cellular Metabolism.

Estrogen-Related Receptor γ Maintains Pancreatic Acinar Cell Function and Identity by Regulating Cellular Metabolism.

Journal: Gastroenterology

Published: August 02, 2021

The translocator protein ligands as mitochondrial functional modulators for the potential anti-Alzheimer agents.

The translocator protein ligands as mitochondrial functional modulators for the potential anti-Alzheimer agents.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: March 23, 2021

Discovery and Biological Evaluation of N-Methyl-pyrrolo[2,3-b]pyridine-5-carboxamide Derivatives as JAK1-Selective Inhibitors.

Discovery and Biological Evaluation of N-Methyl-pyrrolo[2,3-b]pyridine-5-carboxamide Derivatives as JAK1-Selective Inhibitors.

Journal: Journal of medicinal chemistry

Published: January 11, 2021

An orally available inverse agonist of estrogen-related receptor gamma showed expanded efficacy for the radioiodine therapy of poorly differentiated thyroid cancer.

An orally available inverse agonist of estrogen-related receptor gamma showed expanded efficacy for the radioiodine therapy of poorly differentiated thyroid cancer.

Journal: European journal of medicinal chemistry

Published: March 11, 2020

Nrf2 activator via interference of Nrf2-Keap1 interaction has antioxidant and anti-inflammatory properties in Parkinson's disease animal model.

Nrf2 activator via interference of Nrf2-Keap1 interaction has antioxidant and anti-inflammatory properties in Parkinson's disease animal model.

Journal: Neuropharmacology

Published: September 17, 2019

Discovery of BR102375, a new class of non-TZD PPARγ full agonist for the treatment of type 2 diabetes.

Discovery of BR102375, a new class of non-TZD PPARγ full agonist for the treatment of type 2 diabetes.

Journal: Bioorganic & medicinal chemistry letters

Published: February 12, 2019

Showing 1-12 of 27

Last Updated: 09/26/2026