Hazel Sutherland

Institute Of Life Course And Medical Sciences, 6 West Derby Street
Liverpool, ENG L78TX, United Kingdom

Last Updated: 09/26/2026

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Found 25 publications

Specific knockout of kidney homogentisate 1,2-dioxygenase reveals that local metabolism of tyrosine and homogentisic acid is negligible in alkaptonuria.

Specific knockout of kidney homogentisate 1,2-dioxygenase reveals that local metabolism of tyrosine and homogentisic acid is negligible in alkaptonuria.

Journal: Human molecular genetics
Published: January 07, 2026

Repeated Disuse Atrophy Imprints a Molecular Memory in Skeletal Muscle: Transcriptional Resilience in Young Adults and Susceptibility in Aged Muscle.

Repeated Disuse Atrophy Imprints a Molecular Memory in Skeletal Muscle: Transcriptional Resilience in Young Adults and Susceptibility in Aged Muscle.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published: November 10, 2025

Dynamic time course of muscle proteome adaptation to programmed resistance training in rats.

Dynamic time course of muscle proteome adaptation to programmed resistance training in rats.

Journal: American journal of physiology. Cell physiology
Published: October 21, 2025

Skeletal progenitor LRP1 deficiency causes severe and persistent skeletal defects with Wnt pathway dysregulation.

Skeletal progenitor LRP1 deficiency causes severe and persistent skeletal defects with Wnt pathway dysregulation.

Journal: Bone research
Published: March 29, 2024

Hepatobiliary circulation and dominant urinary excretion of homogentisic acid in a mouse model of alkaptonuria.

Hepatobiliary circulation and dominant urinary excretion of homogentisic acid in a mouse model of alkaptonuria.

Journal: Journal of inherited metabolic disease
Published: December 18, 2023

Comprehensive Biotransformation Analysis of Phenylalanine-Tyrosine Metabolism Reveals Alternative Routes of Metabolite Clearance in Nitisinone-Treated Alkaptonuria.

Comprehensive Biotransformation Analysis of Phenylalanine-Tyrosine Metabolism Reveals Alternative Routes of Metabolite Clearance in Nitisinone-Treated Alkaptonuria.

Journal: Metabolites
Published: September 07, 2022

Impact of Nitisinone on the Cerebrospinal Fluid Metabolome of a Murine Model of Alkaptonuria.

Impact of Nitisinone on the Cerebrospinal Fluid Metabolome of a Murine Model of Alkaptonuria.

Journal: Metabolites
Published: May 05, 2022

Metabolomic studies in the inborn error of metabolism alkaptonuria reveal new biotransformations in tyrosine metabolism.

Metabolomic studies in the inborn error of metabolism alkaptonuria reveal new biotransformations in tyrosine metabolism.

Journal: Genes & diseases
Published: November 25, 2020

Anatomical Distribution of Ochronotic Pigment in Alkaptonuric Mice is Associated with Calcified Cartilage Chondrocytes at Osteochondral Interfaces.

Anatomical Distribution of Ochronotic Pigment in Alkaptonuric Mice is Associated with Calcified Cartilage Chondrocytes at Osteochondral Interfaces.

Journal: Calcified tissue international
Published: July 03, 2020

Fractional Synthesis Rates of Individual Proteins in Rat Soleus and Plantaris Muscles.

Fractional Synthesis Rates of Individual Proteins in Rat Soleus and Plantaris Muscles.

Journal: Proteomes
Published: April 02, 2020

Nitisinone causes acquired tyrosinosis in alkaptonuria.

Nitisinone causes acquired tyrosinosis in alkaptonuria.

Journal: Journal of inherited metabolic disease
Published: November 30, 2019

Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria.

Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria.

Journal: Human molecular genetics
Published: July 02, 2019
Showing 1-12 of 25

Last Updated: 09/26/2026