Heidi M. Mcbride

Montreal, QC, Canada

Last Updated: 09/26/2026

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Found 57 publications

An LRRK2 variant blocks NCOA4 trafficking upon iron overload, leading to ferroptotic death.

An LRRK2 variant blocks NCOA4 trafficking upon iron overload, leading to ferroptotic death.

Journal: Journal of cell science
Published: April 21, 2026

Distinct mitochondrial-derived vesicle pathways connect mitochondria with peroxisomes and lysosomes.

Distinct mitochondrial-derived vesicle pathways connect mitochondria with peroxisomes and lysosomes.

Journal: Mitochondrion
Published: March 25, 2026

STING dampens the unfolded protein response to enable the presentation of self-antigens on MHC-I during inflammation.

STING dampens the unfolded protein response to enable the presentation of self-antigens on MHC-I during inflammation.

Journal: Cell reports
Published: January 07, 2026

A single Citrobacter rodentium infection in Pink1 knockout and wild-type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss.

A single Citrobacter rodentium infection in Pink1 knockout and wild-type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss.

Journal: PLoS pathogens
Published: July 09, 2025

Recommendations for mitochondria transfer and transplantation nomenclature and characterization.

Recommendations for mitochondria transfer and transplantation nomenclature and characterization.

Journal: Nature metabolism
Published: August 27, 2024

PINK1 deficiency rewires early immune responses in a mouse model of Parkinson's disease triggered by intestinal infection.

PINK1 deficiency rewires early immune responses in a mouse model of Parkinson's disease triggered by intestinal infection.

Journal: NPJ Parkinson's disease
Published: July 16, 2024

Huntingtin polyglutamine expansions misdirect axonal transport by perturbing motor and adaptor recruitment.

Huntingtin polyglutamine expansions misdirect axonal transport by perturbing motor and adaptor recruitment.

Journal: iScience
Published: April 10, 2024

MAPL regulates gasdermin-mediated release of mtDNA from lysosomes to drive pyroptotic cell death.

MAPL regulates gasdermin-mediated release of mtDNA from lysosomes to drive pyroptotic cell death.

Journal: Nature cell biology
Published: March 07, 2024

MAPL loss dysregulates bile and liver metabolism in mice.

MAPL loss dysregulates bile and liver metabolism in mice.

Journal: EMBO reports
Published: August 10, 2023

Modeling Parkinson's disease pathology in human dopaminergic neurons by sequential exposure to α-synuclein fibrils and proinflammatory cytokines.

Modeling Parkinson's disease pathology in human dopaminergic neurons by sequential exposure to α-synuclein fibrils and proinflammatory cytokines.

Journal: Nature neuroscience
Published: May 29, 2023

Mitochondria-lysosome-related organelles mediate mitochondrial clearance during cellular dedifferentiation.

Mitochondria-lysosome-related organelles mediate mitochondrial clearance during cellular dedifferentiation.

Journal: Cell reports
Published: April 03, 2023

Depletion of LONP2 unmasks differential requirements for peroxisomal function between cell types and in cholesterol metabolism.

Depletion of LONP2 unmasks differential requirements for peroxisomal function between cell types and in cholesterol metabolism.

Journal: Biology direct
Published: March 27, 2023
Showing 1-12 of 57

Last Updated: 09/26/2026