Heino Stass

Clinical PK CV
Wuppertal, NW, Germany

Last Updated: 09/26/2026

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Found 20 publications

Redefining the treatment of Chagas disease: a review of recent clinical and pharmacological data for a novel formulation of nifurtimox.

Redefining the treatment of Chagas disease: a review of recent clinical and pharmacological data for a novel formulation of nifurtimox.

Journal: PLoS neglected tropical diseases

Published: February 25, 2025

Clinical safety and pharmacokinetics of a novel oral niclosamide formulation compared with marketed niclosamide chewing tablets in healthy volunteers: A three-part randomized, double-blind, placebo-controlled trial.

Clinical safety and pharmacokinetics of a novel oral niclosamide formulation compared with marketed niclosamide chewing tablets in healthy volunteers: A three-part randomized, double-blind, placebo-controlled trial.

Journal: PloS one

Published: May 04, 2024

In vivo Metabolism of Nifurtimox and the Drug-Drug Interaction Potential Including its Major Metabolites.

In vivo Metabolism of Nifurtimox and the Drug-Drug Interaction Potential Including its Major Metabolites.

Journal: Current drug metabolism

Published: April 28, 2023

Correction to "Structural and Mechanistic Investigation of the Unusual Metabolism of Nifurtimox".

Correction to "Structural and Mechanistic Investigation of the Unusual Metabolism of Nifurtimox".

Journal: Chemical research in toxicology

Published: April 18, 2023

Structural and Mechanistic Investigation of the Unusual Metabolism of Nifurtimox.

Structural and Mechanistic Investigation of the Unusual Metabolism of Nifurtimox.

Journal: Chemical research in toxicology

Published: October 09, 2022

Nifurtimox for Treatment of Chagas Disease in Pediatric Patients: the Challenges of Applying Pharmacokinetic-Pharmacodynamic Principles to Dose Finding.

Nifurtimox for Treatment of Chagas Disease in Pediatric Patients: the Challenges of Applying Pharmacokinetic-Pharmacodynamic Principles to Dose Finding.

Journal: The AAPS journal

Published: April 19, 2022

Population Pharmacokinetics of Nifurtimox in Adult and Pediatric Patients With Chagas Disease.

Population Pharmacokinetics of Nifurtimox in Adult and Pediatric Patients With Chagas Disease.

Journal: Journal of clinical pharmacology

Published: December 16, 2021

Clinical investigation of the biopharmaceutical characteristics of nifurtimox tablets - Implications for quality control and application.

Clinical investigation of the biopharmaceutical characteristics of nifurtimox tablets - Implications for quality control and application.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Published: March 11, 2021

Safety, tolerability and pharmacokinetics of emodepside, a potential novel treatment for onchocerciasis (river blindness), in healthy male subjects.

Safety, tolerability and pharmacokinetics of emodepside, a potential novel treatment for onchocerciasis (river blindness), in healthy male subjects.

Journal: British journal of clinical pharmacology

Published: August 26, 2020

Biopharmaceutical Characteristics of Nifurtimox Tablets for Age- and Body Weight-Adjusted Dosing in Patients With Chagas Disease.

Biopharmaceutical Characteristics of Nifurtimox Tablets for Age- and Body Weight-Adjusted Dosing in Patients With Chagas Disease.

Journal: Clinical pharmacology in drug development

Published: June 25, 2020

Ciprofloxacin Dry Powder for Inhalation: Inspiratory Flow in Patients with Non-cystic Fibrosis Bronchiectasis.

Ciprofloxacin Dry Powder for Inhalation: Inspiratory Flow in Patients with Non-cystic Fibrosis Bronchiectasis.

Journal: Journal of aerosol medicine and pulmonary drug delivery

Published: March 09, 2019

Application of Physiologically-Based and Population Pharmacokinetic Modeling for Dose Finding and Confirmation During the Pediatric Development of Moxifloxacin.

Application of Physiologically-Based and Population Pharmacokinetic Modeling for Dose Finding and Confirmation During the Pediatric Development of Moxifloxacin.

Journal: CPT: pharmacometrics & systems pharmacology

Published: February 12, 2019

Showing 1-12 of 20

Last Updated: 09/26/2026