Heinz I. Jacobs
Amsterdam, NH, Netherlands
Last Updated: 09/26/2026
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Found 56 publications
Histone methyltransferase DOT1L maintains cell state and restricts cytotoxic potential of CD8 T cells.
Journal: Science advances
Published: December 12, 2025
Epigenetically programmed identity crisis to combat diffuse large B cell lymphoma.
Journal: Trends in immunology
Published: September 03, 2025
Cholesterol biosynthesis as a drug-induced vulnerability in diffuse large B cell lymphoma insensitive to EZH2 inhibition.
Journal: Neoplasia (New York, N.Y.)
Published: July 16, 2025
ADARp150 counteracts whole genome duplication.
Journal: Nucleic acids research
Published: March 08, 2024
Molecular dependencies and genomic consequences of a global DNA damage tolerance defect.
Journal: Genome biology
Published: February 22, 2024
Gemcitabine as chemotherapy of head and neck cancer in Fanconi anemia patients.
Journal: Oncogenesis
Published: August 10, 2023
Dual role of proliferating cell nuclear antigen monoubiquitination in facilitating Fanconi anemia-mediated interstrand crosslink repair.
Journal: PNAS nexus
Published: July 19, 2023
CD4+ T cells produce IFN-I to license cDC1s for induction of cytotoxic T-cell activity in human tumors.
Journal: Cellular & molecular immunology
Published: July 11, 2023
A C57BL/6J Fancg-KO Mouse Model Generated by CRISPR/Cas9 Partially Captures the Human Phenotype.
Journal: International journal of molecular sciences
Published: June 14, 2023
Mammalian life depends on two distinct pathways of DNA damage tolerance.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: January 20, 2023
Last Updated: 09/26/2026