Helen H. Bright

R&D, AstraZeneca
Liverpool, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 20 publications

Harnessing endogenous anti-glycan antibodies using a novel, bifunctional immunotherapy to treat gram-negative bacterial infections.

Harnessing endogenous anti-glycan antibodies using a novel, bifunctional immunotherapy to treat gram-negative bacterial infections.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: August 23, 2024

The SARS-CoV-2 monoclonal antibody combination, AZD7442, is protective in nonhuman primates and has an extended half-life in humans.

The SARS-CoV-2 monoclonal antibody combination, AZD7442, is protective in nonhuman primates and has an extended half-life in humans.

Journal: Science translational medicine

Published: January 25, 2022

The ChAdOx1 vectored vaccine, AZD2816, induces strong immunogenicity against SARS-CoV-2 beta (B.1.351) and other variants of concern in preclinical studies.

The ChAdOx1 vectored vaccine, AZD2816, induces strong immunogenicity against SARS-CoV-2 beta (B.1.351) and other variants of concern in preclinical studies.

Journal: EBioMedicine

Published: September 07, 2021

Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail.

Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail.

Journal: Nature microbiology

Published: July 02, 2021

Defining the root cause of reduced H1N1 live attenuated influenza vaccine effectiveness: low viral fitness leads to inter-strain competition.

Defining the root cause of reduced H1N1 live attenuated influenza vaccine effectiveness: low viral fitness leads to inter-strain competition.

Journal: NPJ vaccines

Published: October 05, 2020

Severity of heterosubtypic influenza virus infection in ferrets is reduced by live attenuated influenza vaccine.

Severity of heterosubtypic influenza virus infection in ferrets is reduced by live attenuated influenza vaccine.

Journal: NPJ vaccines

Published: September 07, 2020

Assessment of the benefits of seasonal influenza vaccination: Elements of a framework to interpret estimates of vaccine effectiveness and support robust decision-making and communication.

Assessment of the benefits of seasonal influenza vaccination: Elements of a framework to interpret estimates of vaccine effectiveness and support robust decision-making and communication.

Journal: Influenza and other respiratory viruses

Published: April 22, 2020

Development of hepatic pathology in GBV-B-infected red-bellied tamarins (Saguinus labiatus).

Development of hepatic pathology in GBV-B-infected red-bellied tamarins (Saguinus labiatus).

Journal: Journal of medical virology

Published: September 16, 2019

Replication of live attenuated influenza vaccine viruses in human nasal epithelial cells is associated with H1N1 vaccine effectiveness.

Replication of live attenuated influenza vaccine viruses in human nasal epithelial cells is associated with H1N1 vaccine effectiveness.

Journal: Vaccine

Published: April 17, 2019

Haemagglutinin stability was not the primary cause of the reduced effectiveness of live attenuated influenza vaccine against A/H1N1pdm09 viruses in the 2013-2014 and 2015-2016 seasons.

Haemagglutinin stability was not the primary cause of the reduced effectiveness of live attenuated influenza vaccine against A/H1N1pdm09 viruses in the 2013-2014 and 2015-2016 seasons.

Journal: Vaccine

Published: February 12, 2019

Structured illumination microscopy combined with machine learning enables the high throughput analysis and classification of virus structure.

Structured illumination microscopy combined with machine learning enables the high throughput analysis and classification of virus structure.

Journal: eLife

Published: July 17, 2018

Letter to the editor: Potential causes of the decreased effectiveness of the influenza A(H1N1)pdm09 strain in live attenuated influenza vaccines.

Letter to the editor: Potential causes of the decreased effectiveness of the influenza A(H1N1)pdm09 strain in live attenuated influenza vaccines.

Journal: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

Published: November 03, 2016

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Last Updated: 09/26/2026