Helen N. Yan

Hong Kong Science Park
Hong Kong, China

Last Updated: 09/26/2026

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Found 18 publications

From regeneration to tumorigenesis: ARID1A as an epigenetic guardian of gastric identity.

From regeneration to tumorigenesis: ARID1A as an epigenetic guardian of gastric identity.

Journal: Developmental cell

Published: May 25, 2026

Exploring WNT pathway dysregulation in serrated colorectal cancer for improved diagnostic and therapeutic strategies.

Exploring WNT pathway dysregulation in serrated colorectal cancer for improved diagnostic and therapeutic strategies.

Journal: Frontiers in genetics

Published: March 06, 2025

A combined enteric neuron-gastric tumor organoid reveals metabolic vulnerabilities in gastric cancer.

A combined enteric neuron-gastric tumor organoid reveals metabolic vulnerabilities in gastric cancer.

Journal: Cell stem cell

Published: January 24, 2025

A covalent inhibitor targeting Cys16 on RhoA in colorectal cancer.

A covalent inhibitor targeting Cys16 on RhoA in colorectal cancer.

Journal: Cell chemical biology

Published: October 02, 2024

Divergent lineage trajectories and genetic landscapes in human gastric intestinal metaplasia organoids associated with early neoplastic progression.

Divergent lineage trajectories and genetic landscapes in human gastric intestinal metaplasia organoids associated with early neoplastic progression.

Journal: Gut

Published: April 05, 2024

The somatic mutation landscape of normal gastric epithelium.

The somatic mutation landscape of normal gastric epithelium.

Journal: Nature

Published: March 11, 2024

Robust analysis of allele-specific copy number alterations from scRNA-seq data with XClone.

Robust analysis of allele-specific copy number alterations from scRNA-seq data with XClone.

Journal: Nature communications

Published: July 20, 2023

Deep Learning-Based 3D Single-Cell Imaging Analysis Pipeline Enables Quantification of Cell-Cell Interaction Dynamics in the Tumor Microenvironment.

Deep Learning-Based 3D Single-Cell Imaging Analysis Pipeline Enables Quantification of Cell-Cell Interaction Dynamics in the Tumor Microenvironment.

Journal: Cancer research

Published: April 11, 2023

Organoid cultures for cancer modeling.

Organoid cultures for cancer modeling.

Journal: Cell stem cell

Published: November 30, 2022

Ganciclovir-induced mutations are present in a diverse spectrum of post-transplant malignancies.

Ganciclovir-induced mutations are present in a diverse spectrum of post-transplant malignancies.

Journal: Genome medicine

Published: July 01, 2022

Escape from cell-cell and cell-matrix adhesion dependence underscores disease progression in gastric cancer organoid models.

Escape from cell-cell and cell-matrix adhesion dependence underscores disease progression in gastric cancer organoid models.

Journal: Gut

Published: February 07, 2022

Mutational landscape of normal epithelial cells in Lynch Syndrome patients.

Mutational landscape of normal epithelial cells in Lynch Syndrome patients.

Journal: Nature communications

Published: October 13, 2021

Showing 1-12 of 18

Last Updated: 09/26/2026