Helen Walden
Glasgow, SCT G128QQ, United Kingdom
Last Updated: 09/26/2026
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Found 47 publications
Stabilising proteins in solution using affordable and readily available small molecules.
Journal: Biophysical reviews
Published: April 14, 2025
Structural and Biochemical Insights into the Mechanism of Action of the Clinical USP1 Inhibitor, KSQ-4279.
Journal: Journal of medicinal chemistry
Published: August 27, 2024
A substrate-interacting region of Parkin directs ubiquitination of the mitochondrial GTPase Miro1.
Journal: The Journal of cell biology
Published: August 05, 2024
Capturing the catalytic intermediates of parkin ubiquitination.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: July 30, 2024
A substrate-interacting region of Parkin directs ubiquitination of the mitochondrial GTPase Miro1.
Journal: bioRxiv : the preprint server for biology
Published: June 19, 2024
The CCP4 suite: integrative software for macromolecular crystallography.
Journal: Acta crystallographica. Section D, Structural biology
Published: March 29, 2023
Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site.
Journal: Science advances
Published: September 28, 2022
Structural and biochemical basis of interdependent FANCI-FANCD2 ubiquitination.
Journal: The EMBO journal
Published: June 16, 2022
Distinct phosphorylation signals drive acceptor versus free ubiquitin chain targeting by parkin.
Journal: The Biochemical journal
Published: October 16, 2021
Last Updated: 09/26/2026