Helena Chaytow
Edinburgh, SCT, United Kingdom
Last Updated: 09/26/2026
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Found 19 publications
Dynamic modulation of the motor neuron translatome during developmental synapse elimination.
Journal: Science signaling
Published: April 15, 2025
Mifepristone alone and in combination with scAAV9-SMN1 gene therapy improves disease phenotypes in Smn2B/- spinal muscular atrophy mice.
Journal: Scientific reports
Published: March 31, 2025
Phosphoglycerate kinase 1 as a therapeutic target in neurological disease.
Journal: Trends in molecular medicine
Published: December 03, 2024
Targeting common disease pathomechanisms to treat amyotrophic lateral sclerosis.
Journal: Nature reviews. Neurology
Published: December 02, 2024
The CCL2-CCR2 axis drives neuromuscular denervation in amyotrophic lateral sclerosis.
Journal: Nature communications
Published: November 07, 2024
Excitotoxicity and ALS: New therapy targets an old mechanism.
Journal: Cell reports. Medicine
Published: January 17, 2024
Long-term muscle-specific overexpression of DOK7 in mice using AAV9-tMCK-DOK7.
Journal: Molecular therapy. Nucleic acids
Published: April 04, 2023
Neuromuscular junction denervation and terminal Schwann cell loss in the hTDP-43 overexpression mouse model of amyotrophic lateral sclerosis.
Journal: Neuropathology and applied neurobiology
Published: March 01, 2023
Targeting phosphoglycerate kinase 1 with terazosin improves motor neuron phenotypes in multiple models of amyotrophic lateral sclerosis.
Journal: EBioMedicine
Published: April 21, 2022
The mitochondrial protein Sideroflexin 3 (SFXN3) influences neurodegeneration pathways in vivo.
Journal: The FEBS journal
Published: November 08, 2021
Last Updated: 09/26/2026