Helena Verdera-Costa
Evry, 91000, France
Last Updated: 09/26/2026
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Found 13 publications
Intravitreal AAV vector delivery induces integrin-dependent ocular inflammation, complement activation, and antiviral and DNA damage responses.
Journal: Frontiers in immunology
Published: January 29, 2026
Identification of alterations of immunometabolism associated with Pompe disease.
Journal: Cellular and molecular life sciences : CMLS
Published: August 20, 2025
AAV vectors trigger DNA damage response-dependent pro-inflammatory signalling in human iPSC-derived CNS models and mouse brain.
Journal: Nature communications
Published: March 26, 2024
Understanding and Tackling Immune Responses to Adeno-Associated Viral Vectors.
Journal: Human gene therapy
Published: September 06, 2023
Hepatic expression of GAA results in enhanced enzyme bioavailability in mice and non-human primates.
Hepatic expression of GAA results in enhanced enzyme bioavailability in mice and non-human primates.
Journal: Nature communications
Published: February 16, 2021
Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses.
Journal: Science translational medicine
Published: June 16, 2020
AAV Vector Immunogenicity in Humans: A Long Journey to Successful Gene Transfer.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: December 27, 2019
Role of Regulatory T Cell and Effector T Cell Exhaustion in Liver-Mediated Transgene Tolerance in Muscle.
Journal: Molecular therapy. Methods & clinical development
Published: August 23, 2019
AAV Gene Transfer with Tandem Promoter Design Prevents Anti-transgene Immunity and Provides Persistent Efficacy in Neonate Pompe Mice.
Journal: Molecular therapy. Methods & clinical development
Published: September 11, 2018
Exposure to wild-type AAV drives distinct capsid immunity profiles in humans.
Journal: The Journal of clinical investigation
Published: May 21, 2018
Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration.
Journal: Nature communications
Published: March 10, 2018
Cellular uptake of extracellular vesicles is mediated by clathrin-independent endocytosis and macropinocytosis.
Journal: Journal of controlled release : official journal of the Controlled Release Society
Published: July 24, 2017
Last Updated: 09/26/2026