Helene Benedetti

Orleans, 45071, France

Last Updated: 09/26/2026

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Found 29 publications

Tetrahydropyridine LIMK inhibitors: Structure activity studies and biological characterization.

Tetrahydropyridine LIMK inhibitors: Structure activity studies and biological characterization.

Journal: European journal of medicinal chemistry

Published: February 16, 2024

An Atypical Mechanism of SUMOylation of Neurofibromin SecPH Domain Provides New Insights into SUMOylation Site Selection.

An Atypical Mechanism of SUMOylation of Neurofibromin SecPH Domain Provides New Insights into SUMOylation Site Selection.

Journal: Journal of molecular biology

Published: January 30, 2024

LIM Kinases: From Molecular to Pathological Features.

LIM Kinases: From Molecular to Pathological Features.

Journal: Cells

Published: June 09, 2023

LIM Kinases, LIMK1 and LIMK2, Are Crucial Node Actors of the Cell Fate: Molecular to Pathological Features.

LIM Kinases, LIMK1 and LIMK2, Are Crucial Node Actors of the Cell Fate: Molecular to Pathological Features.

Journal: Cells

Published: January 30, 2023

Confocal imaging of biomarkers at a single-cell resolution: quantifying 'living' in 3D-printable engineered living material based on Pluronic F-127 and yeast Saccharomyces cerevisiae.

Confocal imaging of biomarkers at a single-cell resolution: quantifying 'living' in 3D-printable engineered living material based on Pluronic F-127 and yeast Saccharomyces cerevisiae.

Journal: Biomaterials research

Published: July 12, 2022

LIM Kinases, Promising but Reluctant Therapeutic Targets: Chemistry and Preclinical Validation In Vivo.

LIM Kinases, Promising but Reluctant Therapeutic Targets: Chemistry and Preclinical Validation In Vivo.

Journal: Cells

Published: June 14, 2022

Re-engineering of CUP1 promoter and Cup2/Ace1 transactivator to convert Saccharomyces cerevisiae into a whole-cell eukaryotic biosensor capable of detecting 10 nM of bioavailable copper.

Re-engineering of CUP1 promoter and Cup2/Ace1 transactivator to convert Saccharomyces cerevisiae into a whole-cell eukaryotic biosensor capable of detecting 10 nM of bioavailable copper.

Journal: Biosensors & bioelectronics

Published: March 22, 2022

Design, Synthesis and SAR in 2,4,7-Trisubstituted Pyrido[3,2-d]Pyrimidine Series as Novel PI3K/mTOR Inhibitors.

Design, Synthesis and SAR in 2,4,7-Trisubstituted Pyrido[3,2-d]Pyrimidine Series as Novel PI3K/mTOR Inhibitors.

Journal: Molecules (Basel, Switzerland)

Published: July 02, 2021

A straightforward methodology to overcome solubility challenges for N-terminal cysteinyl peptide segments used in native chemical ligation.

A straightforward methodology to overcome solubility challenges for N-terminal cysteinyl peptide segments used in native chemical ligation.

Journal: Chemical science

Published: June 24, 2021

The GTPase-activating protein-related domain of neurofibromin interacts with MC1R and regulates pigmentation-mediated signaling in human melanocytes.

The GTPase-activating protein-related domain of neurofibromin interacts with MC1R and regulates pigmentation-mediated signaling in human melanocytes.

Journal: Biochemical and biophysical research communications

Published: October 22, 2020

Neurofibromin Structure, Functions and Regulation.

Neurofibromin Structure, Functions and Regulation.

Journal: Cells

Published: October 01, 2020

Characterization at the Molecular Level using Robust Biochemical Approaches of a New Kinase Protein.

Characterization at the Molecular Level using Robust Biochemical Approaches of a New Kinase Protein.

Journal: Journal of visualized experiments : JoVE

Published: July 16, 2019

Showing 1-12 of 29

Last Updated: 09/26/2026