Helga Schaeff-Ruebsamen
Wuppertal, NW, Germany
Last Updated: 09/26/2026
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Found 27 publications
First-in-Human, Single- and Multiple-Ascending-Dose, Food-Effect, and Absolute Bioavailability Trials to Assess the Pharmacokinetics, Safety, and Tolerability of Pritelivir, a Nonnucleoside Helicase-Primase Inhibitor Against Herpes Simplex Virus in Healthy Subjects.
Journal: Clinical pharmacology in drug development
Published: November 16, 2022
Discovery, Chemistry, and Preclinical Development of Pritelivir, a Novel Treatment Option for Acyclovir-Resistant Herpes Simplex Virus Infections.
Journal: Journal of medicinal chemistry
Published: October 06, 2022
Overcoming fragmentation of health research in Europe: lessons from COVID-19.
Journal: Lancet (London, England)
Published: May 09, 2020
Different solid forms for optimizing route of administration of the herpes drug Pritelivir.
Journal: MedChemComm
Published: April 18, 2019
Pharmacokinetics and Safety of Letermovir and Midazolam Coadministration in Healthy Subjects.
Journal: Clinical pharmacology in drug development
Published: June 06, 2018
The Effect of Oral Letermovir Administration on the Pharmacokinetics of a Single Oral Dose of P-Glycoprotein Substrate Digoxin in Healthy Volunteers.
Journal: Clinical pharmacology in drug development
Published: April 26, 2018
Intravenous Hydroxypropyl β-Cyclodextrin Formulation of Letermovir: A Phase I, Randomized, Single-Ascending, and Multiple-Dose Trial.
Journal: Clinical and translational science
Published: May 04, 2017
Effect of Pritelivir Compared With Valacyclovir on Genital HSV-2 Shedding in Patients With Frequent Recurrences: A Randomized Clinical Trial.
Journal: JAMA
Published: December 21, 2016
Pharmacokinetics and Safety of Letermovir Coadministered With Cyclosporine A or Tacrolimus in Healthy Subjects.
Journal: Clinical pharmacology in drug development
Published: September 16, 2016
Pharmacokinetics and safety of the anti-human cytomegalovirus drug letermovir in subjects with hepatic impairment.
Journal: British journal of clinical pharmacology
Published: June 15, 2016
Pharmacokinetics and safety of letermovir, a novel anti-human cytomegalovirus drug, in patients with renal impairment.
Journal: British journal of clinical pharmacology
Published: May 25, 2016
Acyldepsipeptide antibiotics kill mycobacteria by preventing the physiological functions of the ClpP1P2 protease.
Journal: Molecular microbiology
Published: February 24, 2016
Last Updated: 09/26/2026