Heling Pan

26 Qiuyue Rd
Pudong, 201203, China

Last Updated: 09/26/2026

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Found 18 publications

Enhancing Treg persistence by inhibiting necroptosis restrains autoimmune pathology.

Enhancing Treg persistence by inhibiting necroptosis restrains autoimmune pathology.

Journal: The Journal of clinical investigation

Published: September 01, 2026

PARP12-mediated mono-ADP-ribosylation as a checkpoint for necroptosis and apoptosis.

PARP12-mediated mono-ADP-ribosylation as a checkpoint for necroptosis and apoptosis.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: June 09, 2025

Repression of RIPK1 kinase by INPP5D inhibits expression of diverse proinflammatory mediators and late-onset Alzheimer's disease risk factors.

Repression of RIPK1 kinase by INPP5D inhibits expression of diverse proinflammatory mediators and late-onset Alzheimer's disease risk factors.

Journal: Immunity

Published: March 10, 2025

Cooperation of TRADD- and RIPK1-dependent cell death pathways in maintaining intestinal homeostasis.

Cooperation of TRADD- and RIPK1-dependent cell death pathways in maintaining intestinal homeostasis.

Journal: Nature communications

Published: September 11, 2024

Necroptosis activates UPR sensors without disrupting their binding with GRP78.

Necroptosis activates UPR sensors without disrupting their binding with GRP78.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: August 12, 2021

NEK1-mediated retromer trafficking promotes blood-brain barrier integrity by regulating glucose metabolism and RIPK1 activation.

NEK1-mediated retromer trafficking promotes blood-brain barrier integrity by regulating glucose metabolism and RIPK1 activation.

Journal: Nature communications

Published: February 02, 2021

Caspase inhibition prolongs inflammation by promoting a signaling complex with activated RIPK1.

Caspase inhibition prolongs inflammation by promoting a signaling complex with activated RIPK1.

Journal: The Journal of cell biology

Published: July 21, 2020

Hepatocyte-specific TAK1 deficiency drives RIPK1 kinase-dependent inflammation to promote liver fibrosis and hepatocellular carcinoma.

Hepatocyte-specific TAK1 deficiency drives RIPK1 kinase-dependent inflammation to promote liver fibrosis and hepatocellular carcinoma.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: June 10, 2020

Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners.

Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners.

Journal: Nature communications

Published: May 23, 2020

A dominant autoinflammatory disease caused by non-cleavable variants of RIPK1.

A dominant autoinflammatory disease caused by non-cleavable variants of RIPK1.

Journal: Nature

Published: May 24, 2019

Chaperone-mediated autophagy is involved in the execution of ferroptosis.

Chaperone-mediated autophagy is involved in the execution of ferroptosis.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: February 06, 2019

Corrigendum: SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination.

Corrigendum: SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination.

Journal: Genes & development

Published: December 05, 2018

Showing 1-12 of 18

Last Updated: 09/26/2026