Henk-jan J. Guchelaar

Leiden, ZH, Netherlands

Last Updated: 09/26/2026

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Found 313 publications

Validation of a Text-Mining Tool for Extracting Routine Clinical Care Data in Early-Stage Resectable Non-Small Cell Lung Cancer.

Validation of a Text-Mining Tool for Extracting Routine Clinical Care Data in Early-Stage Resectable Non-Small Cell Lung Cancer.

Journal: JCO clinical cancer informatics

Published: July 29, 2026

Pharmacokinetics of 5-Fluorouracil in Patients Treated With Capecitabine Carrying the c.1236G>A DPYD Variant Allele.

Pharmacokinetics of 5-Fluorouracil in Patients Treated With Capecitabine Carrying the c.1236G>A DPYD Variant Allele.

Journal: JCO precision oncology

Published: June 08, 2026

From Clinical Trials to Real-World Patients: Population Pharmacokinetics and Precision Dosing Simulations of Lorlatinib.

From Clinical Trials to Real-World Patients: Population Pharmacokinetics and Precision Dosing Simulations of Lorlatinib.

Journal: Clinical pharmacokinetics

Published: May 20, 2026

Correction: Model‑Based Alternative Dosing Strategies for Subcutaneous Nivolumab to Improve Cost Effectiveness.

Correction: Model‑Based Alternative Dosing Strategies for Subcutaneous Nivolumab to Improve Cost Effectiveness.

Journal: Clinical pharmacokinetics

Published: May 19, 2026

Model-informed approaches to develop drug cost-saving dosing strategies for pembrolizumab.

Model-informed approaches to develop drug cost-saving dosing strategies for pembrolizumab.

Journal: European journal of cancer (Oxford, England : 1990)

Published: April 10, 2026

Correction: Model‑Based Alternative Dosing Strategies for Subcutaneous Nivolumab to Improve Cost Effectiveness.

Correction: Model‑Based Alternative Dosing Strategies for Subcutaneous Nivolumab to Improve Cost Effectiveness.

Journal: Clinical pharmacokinetics

Published: March 12, 2026

Direct Oral Anticoagulant Levels at Time of Elective Surgery.

Direct Oral Anticoagulant Levels at Time of Elective Surgery.

Journal: JAMA network open

Published: February 04, 2026

Survival of patients with colorectal or pancreatic cancer who received UGT1A1 genotype-guided dosing of irinotecan in the Netherlands (2017-2024): a retrospective, multicentre cohort study.

Survival of patients with colorectal or pancreatic cancer who received UGT1A1 genotype-guided dosing of irinotecan in the Netherlands (2017-2024): a retrospective, multicentre cohort study.

Journal: The Lancet regional health. Europe

Published: November 14, 2025

Real-World Impact of UGT1A1 Genotype-Guided Irinotecan Dosing on Severe Toxicity and Hospitalization: A Multicenter Study.

Real-World Impact of UGT1A1 Genotype-Guided Irinotecan Dosing on Severe Toxicity and Hospitalization: A Multicenter Study.

Journal: Journal of the National Comprehensive Cancer Network : JNCCN

Published: November 05, 2025

Pre-Therapeutic UGT1A1 Genotyping in Breast Cancer Patients Receiving Sacituzumab Govitecan to Improve Safety: A Meta-Analysis and Recommendation.

Pre-Therapeutic UGT1A1 Genotyping in Breast Cancer Patients Receiving Sacituzumab Govitecan to Improve Safety: A Meta-Analysis and Recommendation.

Journal: Clinical and translational science

Published: October 27, 2025

Microbiome-Modulating Strategies in Anticancer Therapy: A Review of Current Evidence and Recommendations for Further Treatment Improvement.

Microbiome-Modulating Strategies in Anticancer Therapy: A Review of Current Evidence and Recommendations for Further Treatment Improvement.

Journal: Probiotics and antimicrobial proteins

Published: October 22, 2025

Predictors of poor treatment tolerability in older patients receiving fluoropyrimidine-based chemotherapy: A prospective cohort study.

Predictors of poor treatment tolerability in older patients receiving fluoropyrimidine-based chemotherapy: A prospective cohort study.

Journal: Journal of geriatric oncology

Published: October 21, 2025

Showing 1-12 of 313

Last Updated: 09/26/2026