Henne H. Holstege

Amsterdam, NH, Netherlands

Last Updated: 09/26/2026

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Found 110 publications

Glial Fibrillary Acidic Protein and Neurofilament Light Reference Intervals in Healthy Individuals.

Glial Fibrillary Acidic Protein and Neurofilament Light Reference Intervals in Healthy Individuals.

Journal: JAMA network open

Published: May 14, 2026

Exome analysis of 22,319 individuals links extremely rare copy-number variants and 22q11.21 dosage to Alzheimer risk.

Exome analysis of 22,319 individuals links extremely rare copy-number variants and 22q11.21 dosage to Alzheimer risk.

Journal: American journal of human genetics

Published: April 20, 2026

Progress towards a biotypic biomarker profile for amyotrophic lateral sclerosis-frontotemporal spectrum disorders.

Progress towards a biotypic biomarker profile for amyotrophic lateral sclerosis-frontotemporal spectrum disorders.

Journal: Brain : a journal of neurology

Published: April 13, 2026

Non-microglial downregulation of PLCG2 impairs synaptic function and elicits Alzheimer disease-related hallmarks.

Non-microglial downregulation of PLCG2 impairs synaptic function and elicits Alzheimer disease-related hallmarks.

Journal: bioRxiv : the preprint server for biology

Published: April 03, 2026

APOE and genetic risk variants influence Alzheimer's disease onset in carriers of an extra copy of APP, with and without Down syndrome.

APOE and genetic risk variants influence Alzheimer's disease onset in carriers of an extra copy of APP, with and without Down syndrome.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: March 10, 2026

Genomics link obesity and type 2 diabetes to Alzheimer's disease to unveil novel biological insights.

Genomics link obesity and type 2 diabetes to Alzheimer's disease to unveil novel biological insights.

Journal: medRxiv : the preprint server for health sciences

Published: February 23, 2026

Genomics link obesity and type 2 diabetes to Alzheimer's disease to unveil novel biological insights.

Genomics link obesity and type 2 diabetes to Alzheimer's disease to unveil novel biological insights.

Journal: medRxiv : the preprint server for health sciences

Published: February 23, 2026

Proteomics of post mortem brains in early- and late-onset Alzheimer's disease: Unraveling differential Aβ effects and potential AD biomarkers.

Proteomics of post mortem brains in early- and late-onset Alzheimer's disease: Unraveling differential Aβ effects and potential AD biomarkers.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: February 02, 2026

Loss of PILRA promotes microglial immunometabolism to reduce amyloid pathology in cell and mouse models of Alzheimer's disease.

Loss of PILRA promotes microglial immunometabolism to reduce amyloid pathology in cell and mouse models of Alzheimer's disease.

Journal: Science translational medicine

Published: December 03, 2025

Genomic analyses reveal new insights into Alzheimer's disease.

Genomic analyses reveal new insights into Alzheimer's disease.

Journal: medRxiv : the preprint server for health sciences

Published: November 24, 2025

Genetic Modifiers of ABCA1 Activity Interact with APOE Isoforms to Mediate Alzheimer's Disease Risk.

Genetic Modifiers of ABCA1 Activity Interact with APOE Isoforms to Mediate Alzheimer's Disease Risk.

Journal: Annals of neurology

Published: October 16, 2025

Assessing the de novo paradigm in sporadic early-onset Alzheimer disease trios.

Assessing the de novo paradigm in sporadic early-onset Alzheimer disease trios.

Journal: Molecular psychiatry

Published: October 02, 2025

Showing 1-12 of 110

Last Updated: 09/26/2026