Henri Benech
Paris, 75013, France
Last Updated: 09/26/2026
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Found 15 publications
New Insights into Drug Development via the Nose-to-Brain Pathway: Exemplification Through Dodecyl Creatine Ester for Neuronal Disorders.
Journal: Pharmaceutics
Published: November 26, 2025
Intranasal delivery of dodecyl creatine ester alleviates motor deficits and increases dopamine levels in a 6-OHDA rat model of parkinsonism.
Journal: Frontiers in aging neuroscience
Published: March 20, 2025
Dodecyl creatine ester, a promising treatment to deliver creatine to neurons, achieves pharmacology efficacy in creatine transporter deficiency.
Journal: European journal of medicinal chemistry
Published: October 21, 2024
Impaired brain glucose metabolism as a biomarker for evaluation of dodecyl creatine ester in creatine transporter deficiency: Insights from patient brain-derived organoids and in vivo [18F]FDG PET imaging in a mouse model.
Journal: Neurobiology of disease
Published: June 04, 2024
Dodecyl creatine ester improves cognitive function and identifies key protein drivers including KIF1A and PLCB1 in a mouse model of creatine transporter deficiency.
Journal: Frontiers in molecular neuroscience
Published: December 07, 2022
Evaluation of a six-probe cocktail (caffeine, tolbutamide, omeprazole, dextromethorphan, midazolam, and digoxin) approach to estimate hepatic drug detoxification capability and dosage requirements after a single oral dosing in healthy Chinese volunteers.
Journal: Naunyn-Schmiedeberg's archives of pharmacology
Published: January 31, 2022
Population Pharmacokinetic Model of Plasma and Cellular Mycophenolic Acid in Kidney Transplant Patients from the CIMTRE Study.
Journal: Drugs in R&D
Published: October 07, 2020
A limited sampling strategy based on maximum a posteriori Bayesian estimation for a five-probe phenotyping cocktail.
Journal: European journal of clinical pharmacology
Published: June 17, 2015
Design optimisation for pharmacokinetic modeling of a cocktail of phenotyping drugs.
Journal: Pharmaceutical statistics
Published: January 30, 2015
Safety and pharmacokinetics of the CIME combination of drugs and their metabolites after a single oral dosing in healthy volunteers.
Journal: European journal of drug metabolism and pharmacokinetics
Published: March 20, 2014
P-glycoprotein, breast cancer resistance protein, Organic Anion Transporter 3, and Transporting Peptide 1a4 during blood-brain barrier maturation: involvement of Wnt/β-catenin and endothelin-1 signaling.
Journal: Molecular pharmaceutics
Published: September 25, 2012
Evaluation of seven drug metabolisms and clearances by cryopreserved human primary hepatocytes cultivated in microfluidic biochips.
Journal: Xenobiotica; the fate of foreign compounds in biological systems
Published: July 27, 2012
Last Updated: 09/26/2026