Hesham Haffez

Cairo, C 11795, Egypt

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 30 publications

The link between diabetes and male infertility: mechanisms and implications.

The link between diabetes and male infertility: mechanisms and implications.

Journal: Scientific reports

Published: April 19, 2026

Thiazole-Derived Dual EGFR/CDK-2 Inhibitors: Rational Design, Synthesis, In Vitro Anticancer Evaluation, Mechanistic Profiling, and Computational Binding Analysis.

Thiazole-Derived Dual EGFR/CDK-2 Inhibitors: Rational Design, Synthesis, In Vitro Anticancer Evaluation, Mechanistic Profiling, and Computational Binding Analysis.

Journal: Archiv der Pharmazie

Published: March 02, 2026

TLR3 polymorphism protects against multiple sclerosis onset but not progression in Egyptian patients.

TLR3 polymorphism protects against multiple sclerosis onset but not progression in Egyptian patients.

Journal: Multiple sclerosis and related disorders

Published: February 18, 2026

Lead Discovery via Scaffold Refinement: Structure-Guided Optimization of 1,2,4-Triazolo[1,5-a]Pyrimidines as Potent Dual EGFR/CDK-2 Inhibitors Targeting Colorectal Carcinoma.

Lead Discovery via Scaffold Refinement: Structure-Guided Optimization of 1,2,4-Triazolo[1,5-a]Pyrimidines as Potent Dual EGFR/CDK-2 Inhibitors Targeting Colorectal Carcinoma.

Journal: Drug development research

Published: January 27, 2026

Towards the discovery of potent epigenetic modulators: Design, synthesis, biological evaluation, and SAR investigation of novel indole-based derivatives targeting HDAC1 and HDAC6.

Towards the discovery of potent epigenetic modulators: Design, synthesis, biological evaluation, and SAR investigation of novel indole-based derivatives targeting HDAC1 and HDAC6.

Journal: Bioorganic chemistry

Published: December 19, 2025

Association of cytokine levels with treatment duration and patient family history in Egyptian multiple sclerosis patients.

Association of cytokine levels with treatment duration and patient family history in Egyptian multiple sclerosis patients.

Journal: Scientific reports

Published: September 19, 2025

Palbociclib in endocrine-resistant metastatic breast cancer patients: gene polymorphism- based study.

Palbociclib in endocrine-resistant metastatic breast cancer patients: gene polymorphism- based study.

Journal: Pharmacological reports : PR

Published: July 10, 2025

Scaffold-hopping strategy for pyrazolo[3,4-d]pyrimidines: In vitro and in silico studies of dual c-Met/STAT3 inhibition for enhanced antitumor activity.

Scaffold-hopping strategy for pyrazolo[3,4-d]pyrimidines: In vitro and in silico studies of dual c-Met/STAT3 inhibition for enhanced antitumor activity.

Journal: Bioorganic chemistry

Published: June 13, 2025

New Fluorescent Synthetic Retinoids as Potential RAR Agonists with Anticancer, Molecular Docking and ADME Assessments.

New Fluorescent Synthetic Retinoids as Potential RAR Agonists with Anticancer, Molecular Docking and ADME Assessments.

Journal: Journal of fluorescence

Published: March 08, 2025

Design and synthesis of novel Hydroxamate and non-Hydroxamate HDAC inhibitors based on Chromone and Quinazolone scaffolds.

Design and synthesis of novel Hydroxamate and non-Hydroxamate HDAC inhibitors based on Chromone and Quinazolone scaffolds.

Journal: Bioorganic chemistry

Published: January 17, 2025

Unravelling the potency of the 4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile scaffold with S-arylamide hybrids as PIM-1 kinase inhibitors: synthesis, biological activity and in silico studies.

Unravelling the potency of the 4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile scaffold with S-arylamide hybrids as PIM-1 kinase inhibitors: synthesis, biological activity and in silico studies.

Journal: RSC medicinal chemistry

Published: January 08, 2025

Synergistic effects of abietic acid combined with doxorubicin on apoptosis induction in a human colorectal cancer cell line.

Synergistic effects of abietic acid combined with doxorubicin on apoptosis induction in a human colorectal cancer cell line.

Journal: Scientific reports

Published: January 07, 2025

Showing 1-12 of 30

Last Updated: 09/26/2026