Hideo Yukioka

Osaka, Japan

Last Updated: 09/26/2026

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Found 19 publications

N-methyl-2-pyridone-5-carboxamide (N-Me-2PY) has potent anti-fibrotic and anti-inflammatory activity in a fibrotic kidney model: is it an old uremic toxin?

N-methyl-2-pyridone-5-carboxamide (N-Me-2PY) has potent anti-fibrotic and anti-inflammatory activity in a fibrotic kidney model: is it an old uremic toxin?

Journal: Clinical and experimental nephrology

Published: December 25, 2022

The significance of NAD + metabolites and nicotinamide N-methyltransferase in chronic kidney disease.

The significance of NAD + metabolites and nicotinamide N-methyltransferase in chronic kidney disease.

Journal: Scientific reports

Published: November 01, 2021

Acsl1 is essential for skin barrier function through the activation of linoleic acid and biosynthesis of ω-O-acylceramide in mice.

Acsl1 is essential for skin barrier function through the activation of linoleic acid and biosynthesis of ω-O-acylceramide in mice.

Journal: Biochimica et biophysica acta. Molecular and cell biology of lipids

Published: July 27, 2021

Acetyl-CoA carboxylase 2 inhibition reduces skeletal muscle bioactive lipid content and attenuates progression of type 2 diabetes in Zucker diabetic fatty rats.

Acetyl-CoA carboxylase 2 inhibition reduces skeletal muscle bioactive lipid content and attenuates progression of type 2 diabetes in Zucker diabetic fatty rats.

Journal: European journal of pharmacology

Published: June 08, 2021

Sphingomyelin synthase 2 loss suppresses steatosis but exacerbates fibrosis in the liver of mice fed with choline-deficient, L-amino acid-defined, high-fat diet.

Sphingomyelin synthase 2 loss suppresses steatosis but exacerbates fibrosis in the liver of mice fed with choline-deficient, L-amino acid-defined, high-fat diet.

Journal: Biochemical and biophysical research communications

Published: September 27, 2020

Diacylglycerol acyltransferase 1/2 inhibition induces dysregulation of fatty acid metabolism and leads to intestinal barrier failure and diarrhea in mice.

Diacylglycerol acyltransferase 1/2 inhibition induces dysregulation of fatty acid metabolism and leads to intestinal barrier failure and diarrhea in mice.

Journal: Physiological reports

Published: May 28, 2020

A Novel Acetyl-CoA Carboxylase 2 Selective Inhibitor Improves Whole-Body Insulin Resistance and Hyperglycemia in Diabetic Mice through Target-Dependent Pathways.

A Novel Acetyl-CoA Carboxylase 2 Selective Inhibitor Improves Whole-Body Insulin Resistance and Hyperglycemia in Diabetic Mice through Target-Dependent Pathways.

Journal: The Journal of pharmacology and experimental therapeutics

Published: November 11, 2019

Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men.

Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men.

Journal: Endocrine journal

Published: November 06, 2019

ACC2 Deletion Enhances IMCL Reduction Along With Acetyl-CoA Metabolism and Improves Insulin Sensitivity in Male Mice.

ACC2 Deletion Enhances IMCL Reduction Along With Acetyl-CoA Metabolism and Improves Insulin Sensitivity in Male Mice.

Journal: Endocrinology

Published: April 10, 2018

An insurmountable NPY Y5 receptor antagonist exhibits superior anti-obesity effects in high-fat diet-induced obese mice.

An insurmountable NPY Y5 receptor antagonist exhibits superior anti-obesity effects in high-fat diet-induced obese mice.

Journal: Neuropeptides

Published: January 26, 2018

The role of acylated-ghrelin in the regulation of sucrose intake.

The role of acylated-ghrelin in the regulation of sucrose intake.

Journal: Endocrine journal

Published: June 28, 2017

NNMT activation can contribute to the development of fatty liver disease by modulating the NAD + metabolism.

NNMT activation can contribute to the development of fatty liver disease by modulating the NAD + metabolism.

Journal: Scientific reports

Published: May 05, 2017

Showing 1-12 of 19

Last Updated: 09/26/2026