Hikari Takeshita

Osaka, Japan

Last Updated: 09/26/2026

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Found 20 publications

Oxidized low-density lipoprotein potentiates angiotensin II-induced Gq activation through the AT1-LOX1 receptor complex.

Oxidized low-density lipoprotein potentiates angiotensin II-induced Gq activation through the AT1-LOX1 receptor complex.

Journal: eLife

Published: March 25, 2025

Analysis of modifying factors for ACE2 to work effectively.

Analysis of modifying factors for ACE2 to work effectively.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension

Published: January 27, 2025

Oxidized LDL enhances Gq signaling and aldosterone production by angiotensin II via the AT1-LOX-1 receptor complex in adrenal cells.

Oxidized LDL enhances Gq signaling and aldosterone production by angiotensin II via the AT1-LOX-1 receptor complex in adrenal cells.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension

Published: January 20, 2025

Muscle mass, muscle strength and the renin-angiotensin system.

Muscle mass, muscle strength and the renin-angiotensin system.

Journal: Clinical science (London, England : 1979)

Published: January 26, 2023

Is the anti-aging effect of ACE2 due to its role in the renin-angiotensin system?-Findings from a comparison of the aging phenotypes of ACE2-deficient, Tsukuba hypertensive, and Mas-deficient mice.

Is the anti-aging effect of ACE2 due to its role in the renin-angiotensin system?-Findings from a comparison of the aging phenotypes of ACE2-deficient, Tsukuba hypertensive, and Mas-deficient mice.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension

Published: March 23, 2022

Tryptophan Metabolism and COVID-19-Induced Skeletal Muscle Damage: Is ACE2 a Key Regulator?

Tryptophan Metabolism and COVID-19-Induced Skeletal Muscle Damage: Is ACE2 a Key Regulator?

Journal: Frontiers in nutrition

Published: February 03, 2022

Double Deletion of Angiotensin II Type 2 and Mas Receptors Accelerates Aging-Related Muscle Weakness in Male Mice.

Double Deletion of Angiotensin II Type 2 and Mas Receptors Accelerates Aging-Related Muscle Weakness in Male Mice.

Journal: Journal of the American Heart Association

Published: July 02, 2021

ACE2, angiotensin 1-7 and skeletal muscle: review in the era of COVID-19.

ACE2, angiotensin 1-7 and skeletal muscle: review in the era of COVID-19.

Journal: Clinical science (London, England : 1979)

Published: July 17, 2020

RAGE ligands stimulate angiotensin II type I receptor (AT1) via RAGE/AT1 complex on the cell membrane.

RAGE ligands stimulate angiotensin II type I receptor (AT1) via RAGE/AT1 complex on the cell membrane.

Journal: Scientific reports

Published: July 07, 2020

The endocytosis of oxidized LDL via the activation of the angiotensin II type 1 receptor.

The endocytosis of oxidized LDL via the activation of the angiotensin II type 1 receptor.

Journal: iScience

Published: June 15, 2020

Different effects of the deletion of angiotensin converting enzyme 2 and chronic activation of the renin-angiotensin system on muscle weakness in middle-aged mice.

Different effects of the deletion of angiotensin converting enzyme 2 and chronic activation of the renin-angiotensin system on muscle weakness in middle-aged mice.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension

Published: July 15, 2019

Angiotensin 1-7 alleviates aging-associated muscle weakness and bone loss, but is not associated with accelerated aging in ACE2-knockout mice.

Angiotensin 1-7 alleviates aging-associated muscle weakness and bone loss, but is not associated with accelerated aging in ACE2-knockout mice.

Journal: Clinical science (London, England : 1979)

Published: May 28, 2019

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Last Updated: 09/26/2026