Hilde D. De Vries

Groningen, GR, Netherlands

Last Updated: 09/26/2026

Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 14 publications

Mice with humanized FXR ligand-binding domain display distinct metabolic responses upon pharmacological FXR stimulation.

Mice with humanized FXR ligand-binding domain display distinct metabolic responses upon pharmacological FXR stimulation.

Journal: Journal of lipid research
Published: May 04, 2026

Bile Acid Detergency as Determinant of Liver Pathology in a Humanized Mouse Model of Progressive Familial Intrahepatic Cholestasis Type 3.

Bile Acid Detergency as Determinant of Liver Pathology in a Humanized Mouse Model of Progressive Familial Intrahepatic Cholestasis Type 3.

Journal: Cellular and molecular gastroenterology and hepatology
Published: October 17, 2025

Bile acid detergency as determinant of liver pathology in a humanized mouse model of progressive familial intrahepatic cholestasis type 3.

Bile acid detergency as determinant of liver pathology in a humanized mouse model of progressive familial intrahepatic cholestasis type 3.

Journal: Cellular and molecular gastroenterology and hepatology
Published: October 17, 2025

Farnesoid x Receptor Deficiency Promotes Hepatocytic Injury in Cyp2c70-Deficient Mice With a Human-Like Bile Acid Composition.

Farnesoid x Receptor Deficiency Promotes Hepatocytic Injury in Cyp2c70-Deficient Mice With a Human-Like Bile Acid Composition.

Journal: Liver international : official journal of the International Association for the Study of the Liver
Published: August 18, 2025

Generation and characterization of a mouse model for bile salt export pump deficiency with the p.E297G mutation.

Generation and characterization of a mouse model for bile salt export pump deficiency with the p.E297G mutation.

Journal: Biochimica et biophysica acta. Molecular and cell biology of lipids
Published: June 12, 2025

Elevated plasma bile acids coincide with cardiac stress and inflammation in young Cyp2c70-/- mice.

Elevated plasma bile acids coincide with cardiac stress and inflammation in young Cyp2c70-/- mice.

Journal: Pediatric research
Published: January 18, 2024

Bile Acid Sequestration via Colesevelam Reduces Bile Acid Hydrophobicity and Improves Liver Pathology in Cyp2c70-/- Mice with a Human-like Bile Acid Composition.

Bile Acid Sequestration via Colesevelam Reduces Bile Acid Hydrophobicity and Improves Liver Pathology in Cyp2c70-/- Mice with a Human-like Bile Acid Composition.

Journal: Biomedicines
Published: August 03, 2023

Gut microbiota depletion aggravates bile acid-induced liver pathology in mice with a human-like bile acid composition.

Gut microbiota depletion aggravates bile acid-induced liver pathology in mice with a human-like bile acid composition.

Journal: Clinical science (London, England : 1979)
Published: July 27, 2023

Role of bile acid receptor FXR in development and function of brown adipose tissue.

Role of bile acid receptor FXR in development and function of brown adipose tissue.

Journal: Biochimica et biophysica acta. Molecular and cell biology of lipids
Published: June 03, 2022

Perinatal exposure to UDCA prevents neonatal cholestasis in Cyp2c70-/- mice with human-like bile acids.

Perinatal exposure to UDCA prevents neonatal cholestasis in Cyp2c70-/- mice with human-like bile acids.

Journal: Pediatric research
Published: March 17, 2022

Low production of 12α-hydroxylated bile acids prevents hepatic steatosis in Cyp2c70-/- mice by reducing fat absorption.

Low production of 12α-hydroxylated bile acids prevents hepatic steatosis in Cyp2c70-/- mice by reducing fat absorption.

Journal: Journal of lipid research
Published: July 13, 2021

Cholangiopathy and Biliary Fibrosis in Cyp2c70-Deficient Mice Are Fully Reversed by Ursodeoxycholic Acid.

Cholangiopathy and Biliary Fibrosis in Cyp2c70-Deficient Mice Are Fully Reversed by Ursodeoxycholic Acid.

Journal: Cellular and molecular gastroenterology and hepatology
Published: September 08, 2020
Showing 1-12 of 14

Last Updated: 09/26/2026