Hirdesh S. Kumar

N.H. 58, Delhi Roorkee Highway, Baghpat Road Bypass Crossing
Meerut, UP 250005, India

Last Updated: 09/26/2026

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Found 19 publications

The AI Revolution: Shaping the Present and Future of Pharmaceutical Research and Development.

The AI Revolution: Shaping the Present and Future of Pharmaceutical Research and Development.

Journal: Reviews on recent clinical trials
Published: November 01, 2025

Multistage protective anti-CelTOS monoclonal antibodies with cross-species sterile protection against malaria.

Multistage protective anti-CelTOS monoclonal antibodies with cross-species sterile protection against malaria.

Journal: Nature communications
Published: February 05, 2024

Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes.

Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes.

Journal: Communications biology
Published: October 10, 2023

Publisher Correction: Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases.

Publisher Correction: Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases.

Journal: Communications biology
Published: May 11, 2023

Structure-Based Design of Bisubstrate Tetracycline Destructase Inhibitors That Block Flavin Redox Cycling.

Structure-Based Design of Bisubstrate Tetracycline Destructase Inhibitors That Block Flavin Redox Cycling.

Journal: Journal of medicinal chemistry
Published: March 06, 2023

Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases.

Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases.

Journal: Communications biology
Published: July 22, 2022

Implications of conformational flexibility, lipid binding, and regulatory domains in cell-traversal protein CelTOS for apicomplexan migration.

Implications of conformational flexibility, lipid binding, and regulatory domains in cell-traversal protein CelTOS for apicomplexan migration.

Journal: The Journal of biological chemistry
Published: May 03, 2022

Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance.

Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance.

Journal: Communications biology
Published: November 20, 2019

A function of profilin in force generation during malaria parasite motility that is independent of actin binding.

A function of profilin in force generation during malaria parasite motility that is independent of actin binding.

Journal: Journal of cell science
Published: October 02, 2019

Getting in: The structural biology of malaria invasion.

Getting in: The structural biology of malaria invasion.

Journal: PLoS pathogens
Published: September 06, 2019

Semisynthetic Analogues of Anhydrotetracycline as Inhibitors of Tetracycline Destructase Enzymes.

Semisynthetic Analogues of Anhydrotetracycline as Inhibitors of Tetracycline Destructase Enzymes.

Journal: ACS infectious diseases
Published: March 06, 2019

Functional genetic evaluation of DNA house-cleaning enzymes in the malaria parasite: dUTPase and Ap4AH are essential in Plasmodium berghei but ITPase and NDH are dispensable.

Functional genetic evaluation of DNA house-cleaning enzymes in the malaria parasite: dUTPase and Ap4AH are essential in Plasmodium berghei but ITPase and NDH are dispensable.

Journal: Expert opinion on therapeutic targets
Published: February 01, 2019
Showing 1-12 of 19

Last Updated: 09/26/2026