Hirokazu Hirai
Maebashi, 3718511, Japan
Last Updated: 09/26/2026
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Found 142 publications
Aromatic-Turmerone Analogs Activate Chaperone-Mediated Autophagy and Ameliorate Dendritic Shrinkage in Purkinje Cell Models of Spinocerebellar Ataxia.
Journal: Biological & pharmaceutical bulletin
Published: May 27, 2026
Establishment of spinocerebellar ataxia type 34 model mice accompanied by early glial activation and degeneration of cerebellar neurons.
Journal: Journal of pharmacological sciences
Published: February 10, 2026
Systematic evaluation of BBB-penetrant AAV capsids in marmosets identifies VCAP-102 as a highly efficient brain-transducing capsid.
Journal: Molecular therapy. Advances
Published: January 05, 2026
Inducible rAAV producer cell lines yield vectors equivalent to transient transfection: a physicochemical and biological comparison.
Journal: Scientific reports
Published: December 23, 2025
Ubiquitous and Brain Cell-Type-Specific Promoters and Enhancers in Lentiviral Vectors.
Journal: Methods in molecular biology (Clifton, N.J.)
Published: November 22, 2025
A compact GAD67 promoter enables inhibitory neuron-targeted AAV gene therapy for seizure suppression.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: November 19, 2025
Manufacture of adeno-associated virus vectors by a novel human-derived cell line HAT and comprehensive evaluation of the vectors.
Journal: Molecular therapy. Advances
Published: September 03, 2025
Blood-brain barrier-penetrant AAV vectors for cell type-specific gene expression in the mouse brain.
Blood-brain barrier-penetrant AAV vectors for cell type-specific gene expression in the mouse brain.
Journal: Anatomical science international
Published: August 27, 2025
Distribution and functional significance of rodent cerebellar glycogen.
Journal: iScience
Published: July 09, 2025
Cerebral blood flow is modulated by astrocytic cAMP elevation independently of IP3R2-mediated Ca2+ signaling in mice.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: July 01, 2025
Age-Progressive Synaptic and Axonal Dysregulation Induced by Purkinje Cell-Targeted AAV Expression of SCA14 PKCγ in Mice.
Journal: Journal of neurochemistry
Published: June 24, 2025
Protocadherin γC4 regulates neuronal survival and dendritic self-avoidance.
Journal: Communications biology
Published: June 19, 2025
Last Updated: 09/26/2026