Hiroshi Fukasawa

Tokyo, 1130033, Japan

Last Updated: 09/26/2026

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Found 10 publications

Design, Synthesis, and Anti-Inflammatory Evaluation of a Novel PPARδ Agonist with a 4-(1-Pyrrolidinyl)piperidine Structure.

Design, Synthesis, and Anti-Inflammatory Evaluation of a Novel PPARδ Agonist with a 4-(1-Pyrrolidinyl)piperidine Structure.

Journal: Journal of medicinal chemistry

Published: August 08, 2023

Discovery and structure-activity relationship study of 2-piperazinyl-benzothiazole derivatives as potent and selective PPARδ agonists.

Discovery and structure-activity relationship study of 2-piperazinyl-benzothiazole derivatives as potent and selective PPARδ agonists.

Journal: Bioorganic & medicinal chemistry

Published: January 15, 2023

Discovery and structure-based design of a new series of potent and selective PPARδ agonists utilizing a virtual screening method.

Discovery and structure-based design of a new series of potent and selective PPARδ agonists utilizing a virtual screening method.

Journal: Bioorganic & medicinal chemistry letters

Published: November 24, 2021

Transdermal administration of aqueous pregabalin solution as a potential treatment option for patients with neuropathic pain to avoid central nervous system-mediated side effects.

Transdermal administration of aqueous pregabalin solution as a potential treatment option for patients with neuropathic pain to avoid central nervous system-mediated side effects.

Journal: Biological & pharmaceutical bulletin

Published: September 13, 2014

Cooperative therapeutic action of retinoic acid receptor and retinoid x receptor agonists in a mouse model of Alzheimer's disease.

Cooperative therapeutic action of retinoic acid receptor and retinoid x receptor agonists in a mouse model of Alzheimer's disease.

Journal: Journal of Alzheimer's disease : JAD

Published: June 12, 2014

Silicon-containing GABA derivatives, silagaba compounds, as orally effective agents for treating neuropathic pain without central-nervous-system-related side effects.

Silicon-containing GABA derivatives, silagaba compounds, as orally effective agents for treating neuropathic pain without central-nervous-system-related side effects.

Journal: ACS chemical neuroscience

Published: April 18, 2014

A novel aromatic carboxylic acid inactivates luciferase by acylation of an enzymatically active regulatory lysine residue.

A novel aromatic carboxylic acid inactivates luciferase by acylation of an enzymatically active regulatory lysine residue.

Journal: PloS one

Published: June 27, 2013

Design, synthesis and evaluation of retinoids with novel bulky hydrophobic partial structures.

Design, synthesis and evaluation of retinoids with novel bulky hydrophobic partial structures.

Journal: Bioorganic & medicinal chemistry

Published: March 30, 2013

(R)- and (S)-4-Amino-3-(trimethylsilyl)methylbutanoic acids ameliorate neuropathic pain without central nervous system-related side effects.

(R)- and (S)-4-Amino-3-(trimethylsilyl)methylbutanoic acids ameliorate neuropathic pain without central nervous system-related side effects.

Journal: Bioorganic & medicinal chemistry letters

Published: September 07, 2012

Tamibarotene: a candidate retinoid drug for Alzheimer's disease.

Tamibarotene: a candidate retinoid drug for Alzheimer's disease.

Journal: Biological & pharmaceutical bulletin

Published: August 07, 2012

Showing 1-10 of 10

Last Updated: 09/26/2026