Hiroshi Shiku

Tsu, 5148507, Japan

Last Updated: 09/26/2026

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Found 98 publications

Changes in the Metabolism of GD2-Specific Murine CAR-T Cells After Co-Culturing with Melanoma.

Changes in the Metabolism of GD2-Specific Murine CAR-T Cells After Co-Culturing with Melanoma.

Journal: International journal of molecular sciences

Published: April 28, 2026

GD2-Specific CAR T Cells Demonstrate Potent and Targeted Anti-Tumor Efficacy Against Melanoma In Vitro and In Vivo.

GD2-Specific CAR T Cells Demonstrate Potent and Targeted Anti-Tumor Efficacy Against Melanoma In Vitro and In Vivo.

Journal: Frontiers in bioscience (Landmark edition)

Published: May 14, 2025

Introducing arginine residues into scFv in CAR-T cells shows promising antitumor effects.

Introducing arginine residues into scFv in CAR-T cells shows promising antitumor effects.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: January 16, 2025

Correction: Fast on-rates of chimeric antigen receptors enhance the sensitivity to peptide MHC via antigen rebinding.

Correction: Fast on-rates of chimeric antigen receptors enhance the sensitivity to peptide MHC via antigen rebinding.

Journal: The Journal of biological chemistry

Published: December 10, 2024

MAGE-A4 pMHC-targeted CAR-T cells exploiting TCR machinery exhibit significantly improved in vivo function while retaining antigen specificity.

MAGE-A4 pMHC-targeted CAR-T cells exploiting TCR machinery exhibit significantly improved in vivo function while retaining antigen specificity.

Journal: Journal for immunotherapy of cancer

Published: October 27, 2024

Decoding NY-ESO-1 TCR T cells: transcriptomic insights reveal dual mechanisms of tumor targeting in a melanoma murine xenograft model.

Decoding NY-ESO-1 TCR T cells: transcriptomic insights reveal dual mechanisms of tumor targeting in a melanoma murine xenograft model.

Journal: Frontiers in immunology

Published: October 07, 2024

Fast on-rates of chimeric antigen receptors enhance the sensitivity to peptide MHC via antigen rebinding.

Fast on-rates of chimeric antigen receptors enhance the sensitivity to peptide MHC via antigen rebinding.

Journal: The Journal of biological chemistry

Published: July 26, 2024

Histological Assessment of Synovial Sarcoma Before and After TCR-T Cell Therapy and Cryoablation: A Case Report.

Histological Assessment of Synovial Sarcoma Before and After TCR-T Cell Therapy and Cryoablation: A Case Report.

Journal: Anticancer research

Published: October 13, 2023

TCR-Engineered Lymphocytes Targeting NY-ESO-1: In Vitro Assessment of Cytotoxicity against Tumors.

TCR-Engineered Lymphocytes Targeting NY-ESO-1: In Vitro Assessment of Cytotoxicity against Tumors.

Journal: Biomedicines

Published: September 29, 2023

Exhaustion, rather than lack of infiltration and persistence, of CAR-T cells hampers the efficacy of CAR-T therapy in an orthotopic PDAC xenograft model.

Exhaustion, rather than lack of infiltration and persistence, of CAR-T cells hampers the efficacy of CAR-T therapy in an orthotopic PDAC xenograft model.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: September 14, 2023

Exploring TCR-like CAR-Engineered Lymphocyte Cytotoxicity against MAGE-A4.

Exploring TCR-like CAR-Engineered Lymphocyte Cytotoxicity against MAGE-A4.

Journal: International journal of molecular sciences

Published: August 04, 2023

CAR-Modified Vγ9Vδ2 T Cells Propagated Using a Novel Bisphosphonate Prodrug for Allogeneic Adoptive Immunotherapy.

CAR-Modified Vγ9Vδ2 T Cells Propagated Using a Novel Bisphosphonate Prodrug for Allogeneic Adoptive Immunotherapy.

Journal: International journal of molecular sciences

Published: May 21, 2023

Showing 1-12 of 98

Last Updated: 09/26/2026