Hirotaka Imai
Tokyo, 1088641, Japan
Last Updated: 09/26/2026
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Found 36 publications
Oxidative Metabolism as a Cause of Lipid Peroxidation in the Execution of Ferroptosis.
Journal: International journal of molecular sciences
Published: June 28, 2024
Retinal pigment epithelium-specific ablation of GPx4 in adult mice recapitulates key features of geographic atrophy in age-related macular degeneration.
Journal: Cell death & disease
Published: April 30, 2024
Deferasirox Targeting Ferroptosis Synergistically Ameliorates Myocardial Ischemia Reperfusion Injury in Conjunction With Cyclosporine A.
Journal: Journal of the American Heart Association
Published: December 29, 2023
Slowly progressive cell death induced by GPx4-deficiency occurs via MEK1/ERK2 activation as a downstream signal after iron-independent lipid peroxidation.
Journal: Journal of clinical biochemistry and nutrition
Published: October 15, 2023
Mitochondria-dependent ferroptosis plays a pivotal role in doxorubicin cardiotoxicity.
Journal: JCI insight
Published: March 22, 2023
Doxorubicin causes ferroptosis and cardiotoxicity by intercalating into mitochondrial DNA and disrupting Alas1-dependent heme synthesis.
Journal: Science signaling
Published: November 01, 2022
Iron Overload via Heme Degradation in the Endoplasmic Reticulum Triggers Ferroptosis in Myocardial Ischemia-Reperfusion Injury.
Journal: JACC. Basic to translational science
Published: February 03, 2022
Mitochondrial glutathione peroxidase 4 is indispensable for photoreceptor development and survival in mice.
Journal: The Journal of biological chemistry
Published: January 21, 2022
Ethoxyquin is a Competent Radical-Trapping Antioxidant for Preventing Ferroptosis in Doxorubicin Cardiotoxicity.
Journal: Journal of cardiovascular pharmacology
Published: January 07, 2022
Impact of Poloxamer 188 Material Attributes on Proteinaceous Visible Particle Formation in Liquid Monoclonal Antibody Formulations.
Journal: Journal of pharmaceutical sciences
Published: December 03, 2021
Detection of material-derived differences in the stiffness of egg yolk phosphatidylcholine-containing liposomes using atomic force microscopy.
Journal: Chemistry and physics of lipids
Published: April 23, 2020
Regulated Necrosis in Pulmonary Disease. A Focus on Necroptosis and Ferroptosis.
Journal: American journal of respiratory cell and molecular biology
Published: February 05, 2020
Last Updated: 09/26/2026