Hirotsugu Hino

Tokyo, 1608402, Japan

Last Updated: 09/26/2026

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Found 22 publications

GAK antagonises ROCK-dependent regulation of actomyosin dynamics.

GAK antagonises ROCK-dependent regulation of actomyosin dynamics.

Journal: Journal of cell science
Published: April 30, 2025

Development of luminescent probes for real-time detection of the CDK/PP2A balance during the cell cycle.

Development of luminescent probes for real-time detection of the CDK/PP2A balance during the cell cycle.

Journal: Genes to cells : devoted to molecular & cellular mechanisms
Published: July 08, 2024

FADS2 confers SCD1 inhibition resistance to cancer cells by modulating the ER stress response.

FADS2 confers SCD1 inhibition resistance to cancer cells by modulating the ER stress response.

Journal: Scientific reports
Published: April 05, 2024

Abemaciclib and Vacuolin-1 decrease aggregate-prone TDP-43 accumulation by accelerating autophagic flux.

Abemaciclib and Vacuolin-1 decrease aggregate-prone TDP-43 accumulation by accelerating autophagic flux.

Journal: Biochemistry and biophysics reports
Published: December 18, 2023

Clarithromycin overcomes stromal cell-mediated drug resistance against proteasome inhibitors in myeloma cells via autophagy flux blockage leading to high NOXA expression.

Clarithromycin overcomes stromal cell-mediated drug resistance against proteasome inhibitors in myeloma cells via autophagy flux blockage leading to high NOXA expression.

Journal: PloS one
Published: May 18, 2023

Imbalanced M1 and M2 Macrophage Polarization in Bone Marrow Provokes Impairment of the Hematopoietic Microenvironment in a Mouse Model of Hemophagocytic Lymphohistiocytosis.

Imbalanced M1 and M2 Macrophage Polarization in Bone Marrow Provokes Impairment of the Hematopoietic Microenvironment in a Mouse Model of Hemophagocytic Lymphohistiocytosis.

Journal: Biological & pharmaceutical bulletin
Published: November 03, 2022

Azithromycin, a potent autophagy inhibitor for cancer therapy, perturbs cytoskeletal protein dynamics.

Azithromycin, a potent autophagy inhibitor for cancer therapy, perturbs cytoskeletal protein dynamics.

Journal: British journal of cancer
Published: August 22, 2022

Abemaciclib and Vacuolin-1 induce vacuole-like autolysosome formation - A new tool to study autophagosome-lysosome fusion.

Abemaciclib and Vacuolin-1 induce vacuole-like autolysosome formation - A new tool to study autophagosome-lysosome fusion.

Journal: Biochemical and biophysical research communications
Published: April 26, 2022

Targeted disruption of GAK stagnates autophagic flux by disturbing lysosomal dynamics.

Targeted disruption of GAK stagnates autophagic flux by disturbing lysosomal dynamics.

Journal: International journal of molecular medicine
Published: April 27, 2021

Age-related exacerbation of hematopoietic organ damage induced by systemic hyper-inflammation in senescence-accelerated mice.

Age-related exacerbation of hematopoietic organ damage induced by systemic hyper-inflammation in senescence-accelerated mice.

Journal: Scientific reports
Published: April 16, 2021

Cytonuclear Estrogen Receptor Alpha Regulates Proliferation and Migration of Endometrial Carcinoma Cells.

Cytonuclear Estrogen Receptor Alpha Regulates Proliferation and Migration of Endometrial Carcinoma Cells.

Journal: The Tokai journal of experimental and clinical medicine
Published: October 16, 2020

Sequestosome 1 (p62) accumulation in breast cancer cells suppresses progesterone receptor expression via argonaute 2.

Sequestosome 1 (p62) accumulation in breast cancer cells suppresses progesterone receptor expression via argonaute 2.

Journal: Biochemical and biophysical research communications
Published: June 24, 2020
Showing 1-12 of 22

Last Updated: 09/26/2026