Hiroyuki Kagechika

Tokyo, Japan

Last Updated: 09/26/2026

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Found 120 publications

Temperature-controlled conformational switching of squaramides enabled by side-chain hydrogen bonding.

Temperature-controlled conformational switching of squaramides enabled by side-chain hydrogen bonding.

Journal: RSC advances

Published: July 15, 2026

A novel selective stabilizer of the ryanodine receptor 2 prevents stress-induced ventricular arrhythmias without impairing cardiac function.

A novel selective stabilizer of the ryanodine receptor 2 prevents stress-induced ventricular arrhythmias without impairing cardiac function.

Journal: British journal of pharmacology

Published: July 30, 2025

Development of Fluorescent Estrogen Receptor Ligands with pH Sensor Functionality.

Development of Fluorescent Estrogen Receptor Ligands with pH Sensor Functionality.

Journal: Chemical & pharmaceutical bulletin

Published: April 29, 2025

An aromatic layered foldamer based on a (cis, cis)-squaramide: chiral induction and absolute structure.

An aromatic layered foldamer based on a (cis, cis)-squaramide: chiral induction and absolute structure.

Journal: Organic & biomolecular chemistry

Published: April 28, 2025

Development of selective RyR2 inhibitors with a pharmacophore containing a parabanic acid skeleton.

Development of selective RyR2 inhibitors with a pharmacophore containing a parabanic acid skeleton.

Journal: RSC medicinal chemistry

Published: February 27, 2025

Development and Mechanistic Evaluation of a Lithocholic Acid Derivative as an Environmentally Safe Rodenticide.

Development and Mechanistic Evaluation of a Lithocholic Acid Derivative as an Environmentally Safe Rodenticide.

Journal: ACS pharmacology & translational science

Published: January 20, 2025

Grandifolins A-D: three 6/6/5 abietane diterpenes and an abietane diterpene from Salvia grandifolia.

Grandifolins A-D: three 6/6/5 abietane diterpenes and an abietane diterpene from Salvia grandifolia.

Journal: Journal of natural medicines

Published: October 19, 2024

Discovery and Structure-Activity Relationship of a Ryanodine Receptor 2 Inhibitor.

Discovery and Structure-Activity Relationship of a Ryanodine Receptor 2 Inhibitor.

Journal: Chemical & pharmaceutical bulletin

Published: April 21, 2024

A potent and selective cis-amide inhibitor of ryanodine receptor 2 as a candidate for cardiac arrhythmia treatment.

A potent and selective cis-amide inhibitor of ryanodine receptor 2 as a candidate for cardiac arrhythmia treatment.

Journal: European journal of medicinal chemistry

Published: September 14, 2023

Anti-Inflammatory Effects of a Novel Nuclear Factor-κB Inhibitory Derivative Derived from Pyrazolo[3,4-d]Pyrimidine in Three Inflammation Models.

Anti-Inflammatory Effects of a Novel Nuclear Factor-κB Inhibitory Derivative Derived from Pyrazolo[3,4-d]Pyrimidine in Three Inflammation Models.

Journal: The Journal of pharmacology and experimental therapeutics

Published: August 28, 2023

An N-Cyanoamide Derivative of Lithocholic Acid Co-Operates with Lysophosphatidic Acid to Promote Human Osteoblast (MG63) Differentiation.

An N-Cyanoamide Derivative of Lithocholic Acid Co-Operates with Lysophosphatidic Acid to Promote Human Osteoblast (MG63) Differentiation.

Journal: Biomolecules

Published: May 20, 2023

Screening for Novel Type 2 Ryanodine Receptor Inhibitors by Endoplasmic Reticulum Ca2+ Monitoring.

Screening for Novel Type 2 Ryanodine Receptor Inhibitors by Endoplasmic Reticulum Ca2+ Monitoring.

Journal: Molecular pharmacology

Published: May 09, 2023

Showing 1-12 of 120

Last Updated: 09/26/2026