Hiroyuki Sumi

Tokyo, Japan

Last Updated: 09/26/2026

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Found 23 publications

Evaluation of Collection and Processing Conditions for Gene Expression Analysis Using Human Myeloid Cells.

Evaluation of Collection and Processing Conditions for Gene Expression Analysis Using Human Myeloid Cells.

Journal: Biopreservation and biobanking

Published: March 25, 2024

Phase 1 dose escalation study of the MDM2 inhibitor milademetan as monotherapy and in combination with azacitidine in patients with myeloid malignancies.

Phase 1 dose escalation study of the MDM2 inhibitor milademetan as monotherapy and in combination with azacitidine in patients with myeloid malignancies.

Journal: Cancer medicine

Published: February 29, 2024

A novel T cell-redirecting anti-GPRC5D × CD3 bispecific antibody with potent antitumor activity in multiple myeloma preclinical models.

A novel T cell-redirecting anti-GPRC5D × CD3 bispecific antibody with potent antitumor activity in multiple myeloma preclinical models.

Journal: Scientific reports

Published: November 08, 2023

Characterization of K-binding factor involved in water-soluble complex of menaquinone-7 produced by Bacillus subtilis natto.

Characterization of K-binding factor involved in water-soluble complex of menaquinone-7 produced by Bacillus subtilis natto.

Journal: Journal of biochemistry

Published: January 04, 2023

A phase 2 study of axicabtagene ciloleucel in relapsed or refractory large B-cell lymphoma in Japan: 1-year follow-up and biomarker analysis.

A phase 2 study of axicabtagene ciloleucel in relapsed or refractory large B-cell lymphoma in Japan: 1-year follow-up and biomarker analysis.

Journal: International journal of hematology

Published: July 21, 2022

Phase I dose-escalation study of milademetan in patients with relapsed or refractory acute myeloid leukemia.

Phase I dose-escalation study of milademetan in patients with relapsed or refractory acute myeloid leukemia.

Journal: International journal of hematology

Published: May 27, 2022

Phase 2 study of axicabtagene ciloleucel in Japanese patients with relapsed or refractory large B-cell lymphoma.

Phase 2 study of axicabtagene ciloleucel in Japanese patients with relapsed or refractory large B-cell lymphoma.

Journal: International journal of clinical oncology

Published: June 30, 2021

Design and synthesis of a monocyclic derivative as a selective ACC1 inhibitor by chemical modification of biphenyl ACC1/2 dual inhibitors.

Design and synthesis of a monocyclic derivative as a selective ACC1 inhibitor by chemical modification of biphenyl ACC1/2 dual inhibitors.

Journal: Bioorganic & medicinal chemistry

Published: December 08, 2020

A novel combination regimen of BET and FLT3 inhibition for FLT3-ITD acute myeloid leukemia.

A novel combination regimen of BET and FLT3 inhibition for FLT3-ITD acute myeloid leukemia.

Journal: Haematologica

Published: January 16, 2020

The identification and pharmacological evaluation of potent, selective and orally available ACC1 inhibitor.

The identification and pharmacological evaluation of potent, selective and orally available ACC1 inhibitor.

Journal: Bioorganic & medicinal chemistry letters

Published: August 17, 2019

Design and synthesis of a novel 1H-pyrrolo[3,2-b]pyridine-3-carboxamide derivative as an orally available ACC1 inhibitor.

Design and synthesis of a novel 1H-pyrrolo[3,2-b]pyridine-3-carboxamide derivative as an orally available ACC1 inhibitor.

Journal: Bioorganic & medicinal chemistry

Published: February 18, 2019

Discovery of Novel Selective Acetyl-CoA Carboxylase (ACC) 1 Inhibitors.

Discovery of Novel Selective Acetyl-CoA Carboxylase (ACC) 1 Inhibitors.

Journal: Journal of medicinal chemistry

Published: December 13, 2017

Showing 1-12 of 23

Last Updated: 09/26/2026