Hisham M. Ibrahim

Toronto, ON M5S1A8, Canada

Last Updated: 09/26/2026

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Found 9 publications

Intracellular accumulation of free cholesterol in macrophages triggers a PARP1 response to DNA damage and PARP1 impairs lipopolysaccharide-induced inflammatory response.

Intracellular accumulation of free cholesterol in macrophages triggers a PARP1 response to DNA damage and PARP1 impairs lipopolysaccharide-induced inflammatory response.

Journal: PloS one
Published: July 09, 2024

Plasma S1P Orchestrates the Reverse Transendothelial Migration of Aortic Intimal Myeloid Cells in Mice.

Plasma S1P Orchestrates the Reverse Transendothelial Migration of Aortic Intimal Myeloid Cells in Mice.

Journal: Arteriosclerosis, thrombosis, and vascular biology
Published: February 08, 2024

Cholesterol accumulation impairs HIF-1α-dependent immunometabolic reprogramming of LPS-stimulated macrophages by upregulating the NRF2 pathway.

Cholesterol accumulation impairs HIF-1α-dependent immunometabolic reprogramming of LPS-stimulated macrophages by upregulating the NRF2 pathway.

Journal: Scientific reports
Published: February 03, 2024

Oxidized Low-Density Lipoprotein Accumulation in Macrophages Impairs Lipopolysaccharide-Induced Activation of AKT2, ATP Citrate Lyase, Acetyl-Coenzyme A Production, and Inflammatory Gene H3K27 Acetylation.

Oxidized Low-Density Lipoprotein Accumulation in Macrophages Impairs Lipopolysaccharide-Induced Activation of AKT2, ATP Citrate Lyase, Acetyl-Coenzyme A Production, and Inflammatory Gene H3K27 Acetylation.

Journal: ImmunoHorizons
Published: November 06, 2023

Oxidized Low-Density Lipoprotein Accumulation Suppresses Glycolysis and Attenuates the Macrophage Inflammatory Response by Diverting Transcription from the HIF-1α to the Nrf2 Pathway.

Oxidized Low-Density Lipoprotein Accumulation Suppresses Glycolysis and Attenuates the Macrophage Inflammatory Response by Diverting Transcription from the HIF-1α to the Nrf2 Pathway.

Journal: Journal of immunology (Baltimore, Md. : 1950)
Published: May 01, 2023

Radiation Impacts Early Atherosclerosis by Suppressing Intimal LDL Accumulation.

Radiation Impacts Early Atherosclerosis by Suppressing Intimal LDL Accumulation.

Journal: Circulation research
Published: January 05, 2021

Erratum: CCL19-CCR7-dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima.

Erratum: CCL19-CCR7-dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima.

Journal: Nature immunology
Published: May 19, 2017

GEF-H1 is necessary for neutrophil shear stress-induced migration during inflammation.

GEF-H1 is necessary for neutrophil shear stress-induced migration during inflammation.

Journal: The Journal of cell biology
Published: March 31, 2016

CCL19-CCR7-dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima.

CCL19-CCR7-dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima.

Journal: Nature immunology
Published: December 08, 2015
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Last Updated: 09/26/2026