Hoi Y. Chu
Sar, China
Last Updated: 09/26/2026
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Found 15 publications
Deciphering the initiation pathway of CagT4SS assembly by in vitro reconstitution of subcomplexes.
Journal: Nature communications
Published: October 30, 2025
Rapid customization of base editors via machine learning-powered combinatorial mutagenesis.
Journal: Molecular cell
Published: September 09, 2025
SplitFusion enables ultrasensitive gene fusion detection and reveals fusion variant-associated tumor heterogeneity.
Journal: Patterns (New York, N.Y.)
Published: November 27, 2024
Quantifying Protein-Nucleic Acid Interactions for Engineering Useful CRISPR-Cas9 Genome-Editing Variants.
Journal: Methods in molecular biology (Clifton, N.J.)
Published: November 14, 2024
Structural insights into the assembly pathway of the Helicobacter pylori CagT4SS outer membrane core complex.
Journal: Structure (London, England : 1993)
Published: March 14, 2024
Author Correction: High-throughput screening of genetic and cellular drivers of syncytium formation induced by the spike protein of SARS-CoV-2.
Journal: Nature biomedical engineering
Published: January 24, 2024
Accurate top protein variant discovery via low-N pick-and-validate machine learning.
Journal: Cell systems
Published: March 21, 2023
Parallel engineering and activity profiling of a base editor system.
Journal: Cell systems
Published: November 29, 2022
High-throughput screening of genetic and cellular drivers of syncytium formation induced by the spike protein of SARS-CoV-2.
Journal: Nature biomedical engineering
Published: November 21, 2022
Machine learning-coupled combinatorial mutagenesis enables resource-efficient engineering of CRISPR-Cas9 genome editor activities.
Journal: Nature communications
Published: September 08, 2021
High-fidelity KKH variant of Staphylococcus aureus Cas9 nucleases with improved base mismatch discrimination.
Journal: Nucleic acids research
Published: August 09, 2021
Last Updated: 09/26/2026