Hong-bo Wang

Key Laboratory Of Molecular Pharmacology And Drug Evaluation
Yantai, 264005, China

Last Updated: 09/26/2026

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Found 30 publications

Dual BRD4/AKT inhibition overcomes c-MYC-driven resistance in metastatic castration-resistant prostate cancer.

Dual BRD4/AKT inhibition overcomes c-MYC-driven resistance in metastatic castration-resistant prostate cancer.

Journal: European journal of medicinal chemistry

Published: February 12, 2026

Inhibition of the ATR-DNAPKcs-RB axis drives G1/S-phase transition and sensitizes triple-negative breast cancer (TNBC) to DNA holliday junctions.

Inhibition of the ATR-DNAPKcs-RB axis drives G1/S-phase transition and sensitizes triple-negative breast cancer (TNBC) to DNA holliday junctions.

Journal: Biochemical pharmacology

Published: February 05, 2024

A novel role for microtubule affinity-regulating kinases in neuropathic pain.

A novel role for microtubule affinity-regulating kinases in neuropathic pain.

Journal: British journal of pharmacology

Published: August 03, 2023

Synthesis and evaluation of piperazinotriazoles. Discovery of a potent and orally bioavailable neurokinin-3 receptor inhibitor.

Synthesis and evaluation of piperazinotriazoles. Discovery of a potent and orally bioavailable neurokinin-3 receptor inhibitor.

Journal: European journal of medicinal chemistry

Published: April 03, 2023

Reproductive and developmental toxicity assessments of LPM3480392, a novel mu opioid receptor biased agonist in rats.

Reproductive and developmental toxicity assessments of LPM3480392, a novel mu opioid receptor biased agonist in rats.

Journal: Reproductive toxicology (Elmsford, N.Y.)

Published: March 24, 2023

Chronic Stress-Induced Elevation of Melanin-Concentrating Hormone in the Locus Coeruleus Inhibits Norepinephrine Production and Associated With Depression-Like Behaviors in Rats.

Chronic Stress-Induced Elevation of Melanin-Concentrating Hormone in the Locus Coeruleus Inhibits Norepinephrine Production and Associated With Depression-Like Behaviors in Rats.

Journal: The international journal of neuropsychopharmacology

Published: January 21, 2023

Identification of a novel heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) ligand that disrupts HnRNPA2B1/nucleic acid interactions to inhibit the MDMX-p53 axis in gastric cancer.

Identification of a novel heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) ligand that disrupts HnRNPA2B1/nucleic acid interactions to inhibit the MDMX-p53 axis in gastric cancer.

Journal: Pharmacological research

Published: December 14, 2022

Synthesis, biological, and structural explorations of a series of μ-opioid receptor (MOR) agonists with high G protein signaling bias.

Synthesis, biological, and structural explorations of a series of μ-opioid receptor (MOR) agonists with high G protein signaling bias.

Journal: European journal of medicinal chemistry

Published: October 08, 2021

VE-822, a novel DNA Holliday junction stabilizer, inhibits homologous recombination repair and triggers DNA damage response in osteogenic sarcomas.

VE-822, a novel DNA Holliday junction stabilizer, inhibits homologous recombination repair and triggers DNA damage response in osteogenic sarcomas.

Journal: Biochemical pharmacology

Published: June 30, 2021

mTOR regulates cocaine-induced behavioural sensitization through the SynDIG1-GluA2 interaction in the nucleus accumbens.

mTOR regulates cocaine-induced behavioural sensitization through the SynDIG1-GluA2 interaction in the nucleus accumbens.

Journal: Acta pharmacologica Sinica

Published: April 10, 2021

Metabolomics, metabolic flux analysis and cancer pharmacology.

Metabolomics, metabolic flux analysis and cancer pharmacology.

Journal: Pharmacology & therapeutics

Published: January 03, 2021

Natural product 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase.

Natural product 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase.

Journal: Acta pharmacologica Sinica

Published: December 17, 2020

Showing 1-12 of 30

Last Updated: 09/26/2026