Hong L. Heng

Singapore, 168583, Singapore

Last Updated: 09/26/2026

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Found 18 publications

Uncovering BAP1 deubiquitination landscape enhances mechanism elucidation and therapeutic precision for BAP1-deficient pancancers.

Uncovering BAP1 deubiquitination landscape enhances mechanism elucidation and therapeutic precision for BAP1-deficient pancancers.

Journal: Science translational medicine

Published: April 01, 2026

Integrative genomic, transcriptomic, and metabolomic profiling of Dillenia suffruticosa.

Integrative genomic, transcriptomic, and metabolomic profiling of Dillenia suffruticosa.

Journal: Scientific reports

Published: April 23, 2025

Synergistic suppression of cholangiocarcinoma cells via DNA damage response and cell cycle arrest by dual targeting PARP and ATM in DNA damage repair pathway.

Synergistic suppression of cholangiocarcinoma cells via DNA damage response and cell cycle arrest by dual targeting PARP and ATM in DNA damage repair pathway.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: February 25, 2025

PARP inhibitor augments anti-tumor efficacy of DNMT inhibitor by inducing senescence in cholangiocarcinoma.

PARP inhibitor augments anti-tumor efficacy of DNMT inhibitor by inducing senescence in cholangiocarcinoma.

Journal: International journal of biological sciences

Published: January 23, 2025

ZNF395 Is a Hypoxia-Responsive Regulator of Mitochondrial Glutaminolysis in Clear Cell Renal Cell Carcinoma.

ZNF395 Is a Hypoxia-Responsive Regulator of Mitochondrial Glutaminolysis in Clear Cell Renal Cell Carcinoma.

Journal: Cancer research

Published: December 09, 2024

Effects of RARα ligand binding domain mutations on breast fibroepithelial tumor function and signaling.

Effects of RARα ligand binding domain mutations on breast fibroepithelial tumor function and signaling.

Journal: NPJ breast cancer

Published: August 10, 2024

Establishment and genomic profiling of cholangiocarcinoma cells with functional characterization.

Establishment and genomic profiling of cholangiocarcinoma cells with functional characterization.

Journal: Scientific reports

Published: August 05, 2024

Cholangiocarcinoma: Recent Advances in Molecular Pathobiology and Therapeutic Approaches.

Cholangiocarcinoma: Recent Advances in Molecular Pathobiology and Therapeutic Approaches.

Journal: Cancers

Published: January 11, 2024

Integrative multiomics enhancer activity profiling identifies therapeutic vulnerabilities in cholangiocarcinoma of different etiologies.

Integrative multiomics enhancer activity profiling identifies therapeutic vulnerabilities in cholangiocarcinoma of different etiologies.

Journal: Gut

Published: June 13, 2023

PBRM1-deficient PBAF complexes target aberrant genomic loci to activate the NF-κB pathway in clear cell renal cell carcinoma.

PBRM1-deficient PBAF complexes target aberrant genomic loci to activate the NF-κB pathway in clear cell renal cell carcinoma.

Journal: Nature cell biology

Published: May 25, 2021

Functional characterisation guides classification of novel BAP1 germline variants.

Functional characterisation guides classification of novel BAP1 germline variants.

Journal: NPJ genomic medicine

Published: June 05, 2020

Genomic and proteomic characterization of ARID1A chromatin remodeller in ampullary tumors.

Genomic and proteomic characterization of ARID1A chromatin remodeller in ampullary tumors.

Journal: American journal of cancer research

Published: December 18, 2016

Showing 1-12 of 18

Last Updated: 09/26/2026